1-(Thiolan-3-yl)piperidine-4-carboxylic acid hydrochloride CAS 1185299-73-3
| CAS No. | 1185299-73-3 |
| Molecular Formula | C10H17NO2S |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
1-(Thiolan-3-yl)piperidine-4-carboxylic acid hydrochloride (CAS 1185299-73-3), molecular formula C10H17NO2SHCl and molecular weight 251.77 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 1-(Thiolan-3-yl)piperidine-4-carboxylic acid hydrochloride (C10H17NO2SHCl) is characterized by an amide group, a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H17NO2S HCl |
| Molecular Weight | 251.77 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Thiolan Standards
- (3R)-thiolan-3-ol (CAS 100937-75-5)
- (thiolan-3-yl)hydrazine (CAS 1016709-16-2)
- thiolan-3-amine (CAS 101993-01-5)
- 1-(Thiolan-3-yl)ethan-1-one (CAS 105850-94-0)
- 2-[methyl(thiolan-3-yl)amino]acetic acid (CAS 1095626-10-0)
- [(Thiolan-2-yl)methyl]thiourea (CAS 1252797-66-2)
- Methyl[(thiolan-2-yl)methyl]amine (CAS 1339646-28-4)
- [(thiolan-3-yl)methyl]hydrazine (CAS 1343167-64-5)
Recommended Standards
- 5-Cyclopropoxy-2-fluorobenzamide (CAS 1243407-77-3)
- 4-Chloro-6-fluoro-2-(methylthio)quinazoline (CAS 864293-08-3)
- 2-(1-Methylpiperidin-3-yl)ethan-1-amine (CAS 53295-72-0)
- 1225443-54-8 9-(~2~H_3_)Methyl-1,2,3,9-tetrahydro-4H-carbazol-4-one DTXSID90731513 (CAS 1225443-54-8)
- Azide-PEG4-Tos (CAS 168640-82-2)
- (S)-1-(3-chloro-4-methylphenyl)butan-1-amine (CAS 1213405-27-6)
- 2-(3-Methoxynaphthalen-2-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 2225873-39-0)
- 2-Cyclopentylbenzofuran-5-carboxylic acid methyl ester (CAS 1154060-72-6)
- Levetiracetam (CAS 102767-28-2)
- Peptide YY (human) trifluoroacetate salt (CAS 118997-30-1)
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