1-(Thiazol-2-yl)piperidin-4-amine hydrochloride CAS 1185319-77-0
| CAS No. | 1185319-77-0 |
| Molecular Formula | C8H13N3S |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 1-(Thiazol-2-yl)piperidin-4-amine hydrochloride (C8H13N3SHCl) is characterized by a nitrile group, sulfur-containing functionality, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
1-(Thiazol-2-yl)piperidin-4-amine hydrochloride (CAS 1185319-77-0), molecular formula C8H13N3SHCl and molecular weight 219.73 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H13N3S HCl |
| Molecular Weight | 219.73 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Thiazol Standards
- (2-Methyl-1,3-thiazol-4-yl)methanesulfonyl chloride (CAS 1000394-87-5)
- 3-(Thiazol-5-yl)propan-1-ol (CAS 1000527-93-4)
- 3-(2-Methyl-1,3-thiazol-4-yl)propan-1-amine (CAS 1000538-65-7)
- 2-[(5-methyl-1,3-thiazol-2-yl)thio]-1-thien-2-ylethanone (CAS 1000932-25-1)
- 1-[(5-methyl-1,3-thiazol-2-yl)thio]acetone (CAS 1000932-28-4)
- 3-(Thiazol-2-yl)propanoyl chloride (CAS 1001185-54-1)
- 1-(4-Methyl-1,3-thiazol-2-yl)prop-2-en-1-one (CAS 1003313-20-9)
- 5-Oxo-5-(thiazol-2-ylamino)pentanoic acid (CAS 100377-67-1)
Recommended Standards
- 1-(3-Chlorophenyl)-2-(pyridin-4-yl)ethanone (CAS 125996-70-5)
- 5,6,7,8-Tetrahydroimidazo[2',1':2,3]thiazolo[5,4-c]pyridine (CAS 74004-53-8)
- 1-Benzhydryl-3-isopropylazetidin-3-ol (CAS 848192-91-6)
- 2-Chlorobenzene-1,3,5-trisulfonyl trifluoride (CAS 1342799-69-2)
- N-(3-Amino-2-methylphenyl)-2-(4-chloro-3,5-dimethylphenoxy)acetamide (CAS 1020056-26-1)
- 2-Acetyl-6-benzyl-N,N-dimethyl-2,6-diazaspiro[3.4]octane-8-carboxamide (CAS 1956319-02-0)
- (E)-N-Phenyl-1-(5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)thiophen-2-yl)methanimine (CAS 1257651-22-1)
- Ethyl 2-amino-3-ethoxy-5-fluorobenzoate (CAS 1354963-63-5)
- 6-Fluoro-3-methyl-2,3-dihydro-1H-inden-1-one (CAS 162549-02-2)
- Semaglutide Impurity 183 (CAS 159541-28-3)
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