1-Methoxy-N,N,N',N'-tetramethylmethanediamine CAS 1186-70-5

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 1-Methoxy-N,N,N',N'-tetramethylmethanediamine.

1-Methoxy-N,N,N',N'-tetramethylmethanediamine (CAS 1186-70-5) is a high-purity analytical reference standard with the molecular formula C6H16N2O and a molecular weight of 132.20 g/mol.

The molecular framework of 1-Methoxy-N,N,N',N'-tetramethylmethanediamine (C6H16N2O) is characterized by an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 1-Methoxy-N,N,N',N'-tetramethylmethanediamine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

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