1-Amino-3,3-bis(trifluoromethyl)cyclobutane-1-carboxylic acid CAS 1186237-66-0
| CAS No. | 1186237-66-0 |
| Molecular Formula | C7H7F6NO2 |
| Molecular Weight | 251.13 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 1-Amino-3,3-bis(trifluoromethyl)cyclobutane-1-carboxylic acid.
CATO supplies 1-Amino-3,3-bis(trifluoromethyl)cyclobutane-1-carboxylic acid (CAS 1186237-66-0), a certified reference material (molecular formula C7H7F6NO2, MW 251.13 g/mol) for analytical method development and quality control.
Structurally, 1-Amino-3,3-bis(trifluoromethyl)cyclobutane-1-carboxylic acid (C7H7F6NO2) contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 2.0, corresponding to approximately 2 ring(s) or double-bond equivalent(s). With a molecular weight of 251.13 g/mol, it falls into the medium-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C7H7F6NO2 |
| Molecular Weight | 251.13 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
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