5-Chlorobiphenyl-3-ylboronic acid CAS 1186403-21-3
| CAS No. | 1186403-21-3 |
| Molecular Formula | C12H10BClO2 |
| Molecular Weight | 232.47 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO supplies 5-Chlorobiphenyl-3-ylboronic acid (CAS 1186403-21-3), a certified reference material (molecular formula C12H10BClO2, MW 232.47 g/mol) for analytical method development and quality control.
The molecular framework of 5-Chlorobiphenyl-3-ylboronic acid (C12H10BClO2) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
CATO manufactures 5-Chlorobiphenyl-3-ylboronic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C12H10BClO2 |
| Molecular Weight | 232.47 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | Cl-containing |
Related Chlorobiphenyl Standards
- 3’-Chlorobiphenyl-4-boronic Acid (CAS 1025496-32-5)
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- 4-Chlorobiphenyl-2-boronic acid (CAS 544678-60-6)
- 4’-Chlorobiphenyl-3-carboxylic Acid (CAS 4655-10-1)
- 1-(3-Chlorobiphenyl-3-yl)-ethylamine (CAS 1247711-55-2)
- (4-Chlorobiphenyl-2-yl)-acetonitrile (CAS 1357575-73-5)
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Recommended Standards
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- 6-((tert-Butoxycarbonyl)amino)-1H-indole-2-carboxylic acid (CAS 1093261-27-8)
- 3-Amino-6-(4-methyl-1-piperazinyl)pyridazine (CAS 66346-94-9)
- 1-(5-Bromo-6-chloropyridin-3-yl)ethan-1-one (CAS 1211534-26-7)
- 1-(4-Iodo-3-methyl-1H-pyrazol-1-yl)propan-2-one (CAS 1354703-43-7)
- 2-(6-Acetyl-4-chloropyridin-2-yl)acetic acid (CAS 1393539-80-4)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com