2-(2-Fluoro-4-(trifluoromethyl)phenyl)-4-methylthiazole-5-carboxylic acid CAS 1186404-90-9

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-(2-Fluoro-4-(trifluoromethyl)phenyl)-4-methylthiazole-5-carboxylic acid.

2-(2-Fluoro-4-(trifluoromethyl)phenyl)-4-methylthiazole-5-carboxylic acid (CAS 1186404-90-9), molecular formula C12H7F4NO2S and molecular weight 305.25 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of 2-(2-Fluoro-4-(trifluoromethyl)phenyl)-4-methylthiazole-5-carboxylic acid (C12H7F4NO2S) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.

CATO manufactures 2-(2-Fluoro-4-(trifluoromethyl)phenyl)-4-methylthiazole-5-carboxylic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

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