2,4-Dichloro-5,6-dihydrobenzo[h]quinazoline CAS 1186410-71-8
| CAS No. | 1186410-71-8 |
| Molecular Formula | C12H8Cl2N2 |
| Molecular Weight | 251.11 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
2,4-Dichloro-5,6-dihydrobenzo[h]quinazoline (CAS 1186410-71-8) is a high-purity analytical reference standard with the molecular formula C12H8Cl2N2 and a molecular weight of 251.11 g/mol.
The molecular framework of 2,4-Dichloro-5,6-dihydrobenzo[h]quinazoline (C12H8Cl2N2) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C12H8Cl2N2 |
| Molecular Weight | 251.11 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Dichloro Standards
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- 3',4'-Dichloro-[1,1'-biphenyl]-3-carbaldehyde (CAS 476490-05-8)
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Recommended Standards
- 1-(Dichloromethyl)dibenzo[b,d]furan (CAS 139781-07-0)
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- Raloxifene Impurity 29 (CAS 68574-35-6)
- (1S)-1-(2,2-difluorobenzo[d]1,3-dioxolen-4-yl)ethylamine (CAS 1213390-36-3)
- 2,6-dimethyldihydro-2h-pyran-4(3h)-one (CAS 1073-79-6)
- 1-(4-Bromophenyl)-2-ethyl-1H-benzo[d]imidazole (CAS 97870-64-9)
- 1-benzyl-3,3-dimethylpiperazin-2-one hydrochloride (CAS 23914-09-2)
- 4-Hydroxypyridine 1-oxide (CAS 6890-62-6)
- 3-Amino-5,6,7,8,9,10-hexahydrocycloocta[b]thieno[3,2-e]pyridine-2-carbonitrile (CAS 166113-91-3)
- 3-Bromo-2-chloro-5-fluorophenol (CAS 1805479-20-2)
- Ethyl (2-cyano-4-nitrophenyl)glycinate (CAS 1158272-89-9)
- 2-Hydroxy-4,6-diphenylnicotinonitrile (CAS 16232-42-1)
- Des-Ile17-Tirzepatide (CAS CATO-CPTD788956)
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