H-Tyr-Gly-Trp-OH (H-5475.1000) CAS 118643-55-3
| CAS No. | 118643-55-3 |
| Molecular Formula | C22H24N4O5 |
| Molecular Weight | 424.45 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 424.45 g/mol gives H-Tyr-Gly-Trp-OH (H-5475.1000) distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
H-Tyr-Gly-Trp-OH (H-5475.1000) (CAS 118643-55-3) is a high-purity analytical reference standard with the molecular formula C22H24N4O5 and a molecular weight of 424.45 g/mol.
The molecular framework of H-Tyr-Gly-Trp-OH (H-5475.1000) (C22H24N4O5) is characterized by a flavonoid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C22H24N4O5 |
| Molecular Weight | 424.45 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Nitrogen Atoms | 4 |
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