(6-Chloropyridin-3-yl)(2,3-dimethoxyphenyl)methanone CAS 1187168-38-2
| CAS No. | 1187168-38-2 |
| Molecular Formula | C14H12ClNO3 |
| Molecular Weight | 277.70 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of (6-Chloropyridin-3-yl)(2,3-dimethoxyphenyl)methanone (C14H12ClNO3) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
(6-Chloropyridin-3-yl)(2,3-dimethoxyphenyl)methanone (CAS 1187168-38-2) is a high-purity analytical reference standard with the molecular formula C14H12ClNO3 and a molecular weight of 277.70 g/mol.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C14H12ClNO3 |
| Molecular Weight | 277.70 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Chloropyridin Standards
- (6-Chloropyridin-3-yl)(2,6-dimethoxyphenyl)methanone (CAS 1187168-44-0)
- (6-Chloropyridin-3-yl)(2,5-dimethoxyphenyl)methanone (CAS 1187169-52-3)
- (6-Chloropyridin-3-yl)(2,4-dimethoxyphenyl)methanone (CAS 122628-36-8)
- 2-{2-[(3-chloropyridin-4-yl)methoxy]phenyl}acetic acid (CAS 1500880-56-7)
- 2-(4-((6-Chloropyridin-3-yl)methoxy)phenyl)acetic acid (CAS 860784-49-2)
- 4-((6-Chloropyridin-3-yl)methoxy)-3-methoxybenzaldehyde (CAS 860644-64-0)
- Methyl 4-((6-chloropyridin-3-yl)methoxy)benzoate (CAS 865660-08-8)
- Methyl 1-(6-chloropyridin-2-yl)-5-cyclopropyl-1H-pyrazole-4-carboxylate (CAS 1150164-34-3)
Recommended Standards
- (1E)-2-Chloro-N-[(4-morpholin-4-yl-4-oxobutanoyl)oxy]ethanimidamide (CAS 1119452-85-5)
- 4-Amino-3-((4-chlorobenzyl)oxy)benzoic acid (CAS 1096330-77-6)
- 7-Chloro-1-cyclopropyl-1,4-dihydro-8-methyl-4-oxo-3-quinolinecarboxylic Acid (CAS 103877-20-9)
- 2-Chloro-5-(3,5-dimethoxybenzoyl)pyridine (CAS 1187169-82-9)
- Methyl 4,5,6,7-tetrahydropyrazolo[1,5-a]pyrazine-2-carboxylate hydrochloride (CAS 2055405-85-9)
- (2-(tert-Butyl)-5-(methylthio)oxazol-4-yl)triphenylphosphonium iodide (CAS 122418-68-2)
- 1-(Methylsulfonyl)-4-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzyl)piperazine (CAS 1206641-59-9)
- Amoxicillin Impurity 23 (CAS CATO-C4X-114823)
- Ethyl 7-((7-methoxy-4-oxo-3,4-dihydroquinazolin-6-yl)oxy)heptanoate (CAS 1012057-25-8)
- 3-(3-Ethoxyphenyl)-N'-(3-methoxybenzylidene)-1H-pyrazole-5-carbohydrazide (CAS 302917-94-8)
- 4-Chloro-2-(((2,5-dimethoxybenzyl)amino)methyl)phenol (CAS 1232801-83-0)
- 1-(4-Trifluoromethylphenyl)piperazine 1-(4-trifluoromethyl-phenyl)-piperazine 1-(4-trifluoromethylphenyl)-piperazine 1-[4-(trifluoromethyl)phenyl]piperazine 30459-17-7 n-(4-trifluoro methyl phenyl) piperazine n-(4-trifluoromethylphenyl)piperazine n-(alpha,alpha,alpha-trifluoro-p-tolyl)piperazine (CAS 30459-17-7)
- Phenyl(tetrahydrofuran-3-yl)methanone (CAS 1248356-66-2)
- Acetyl-Tau Peptide (273-284) amide trifluoroacetate salt (CAS 1684399-52-7)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com