4-(3,4,5-trifluorobenzoyl)isoquinoline CAS 1187169-84-1
| CAS No. | 1187169-84-1 |
| Molecular Formula | C16H8F3NO |
| Molecular Weight | 287.24 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO supplies 4-(3,4,5-trifluorobenzoyl)isoquinoline (CAS 1187169-84-1), a certified reference material (molecular formula C16H8F3NO, MW 287.24 g/mol) for analytical method development and quality control.
The molecular framework of 4-(3,4,5-trifluorobenzoyl)isoquinoline (C16H8F3NO) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
CATO manufactures 4-(3,4,5-trifluorobenzoyl)isoquinoline under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C16H8F3NO |
| Molecular Weight | 287.24 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related trifluorobenzoyl Standards
- 4-(3,4,5-Trifluorobenzoyl)quinoline (CAS 1706462-49-8)
- Methyl 2-(3,4,5-trifluorobenzoyl)benzoate (CAS 1443331-20-1)
- 3-(3,4,5-Trifluorobenzoyl)phenyl acetate (CAS 890099-23-7)
- 4-(3,4,5-Trifluorobenzoyl)phenyl acetate (CAS 890100-39-7)
- 2-(3,4,5-Trifluorobenzoyl)benzoic acid (CAS 1417514-72-7)
- 4-(2,4,6-Trifluorobenzoyl)-1H-pyrrole-2-carboxylic acid (CAS 1201597-19-4)
- 5-Methyl-2-(3,4,5-trifluorobenzoyl)pyridine (CAS 1187163-74-1)
- 4-Methyl-3-(3,4,5-trifluorobenzoyl)pyridine (CAS 1187164-39-1)
Recommended Standards
- Quinolin-3-yl(3,4,5-trifluorophenyl)methanone (CAS 1187168-56-4)
- Cyanidin (CAS 13306-05-3)
- tert-Butyl (6-cyano-5-(trifluoromethyl)pyridin-3-yl)carbamate (CAS 1165744-14-8)
- Ethyl 3-amino-1-methyl-6-(trifluoromethyl)-1H-pyrrolo[3,2-b]pyridine-2-carboxylate (CAS 1370587-21-5)
- ethyl (2Z)-3-[(2-chloro-4-fluorophenyl)amino]-2-cyanoprop-2-enoate (CAS 1181467-86-6)
- 3-(2-Bromo-6-(trifluoromethyl)phenyl)thiazolidine (CAS 1774895-77-0)
- n-(Benzo[d][1,3]dioxol-5-ylmethyl)pyrazin-2-amine (CAS 930859-14-6)
- 2-(4-(1H-Pyrazol-1-yl)benzyl)isothiazol-3(2H)-one (CAS 918108-08-4)
- 2-Ethyl-1-benzofuran-3-carbaldehyde (CAS 10035-41-3)
- 2-(4-Chlorophenyl)pyrimidin-4-amine (CAS 114523-63-6)
- 2-[(4-hydroxyphenyl)sulfanyl]acetic acid (CAS 42580-38-1)
- Gentamicin C1a (CAS 26098-04-4)
- Oxan-4-ylmethanethiol (CAS 1250046-08-2)
- Tirzepatide Impurity 59 (CAS CATO-C4X-324059)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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