(3,5-Difluorophenyl)(4-methylpyridin-3-yl)methanone CAS 1187170-91-7

Description

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

(3,5-Difluorophenyl)(4-methylpyridin-3-yl)methanone (CAS 1187170-91-7) is a high-purity analytical reference standard with the molecular formula C13H9F2NO and a molecular weight of 233.21 g/mol.

The molecular framework of (3,5-Difluorophenyl)(4-methylpyridin-3-yl)methanone (C13H9F2NO) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

As a certified reference material (CRM), (3,5-Difluorophenyl)(4-methylpyridin-3-yl)methanone meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

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