1-(tert-Butoxycarbonyl)-4-(2-chlorobenzyl)piperidine-4-carboxylic acid CAS 1187173-46-1
| CAS No. | 1187173-46-1 |
| Molecular Formula | C18H24ClNO4 |
| Molecular Weight | 353.84 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 1-(tert-Butoxycarbonyl)-4-(2-chlorobenzyl)piperidine-4-carboxylic acid.
1-(tert-Butoxycarbonyl)-4-(2-chlorobenzyl)piperidine-4-carboxylic acid (CAS 1187173-46-1) is a high-purity analytical reference standard with the molecular formula C18H24ClNO4 and a molecular weight of 353.84 g/mol.
The molecular framework of 1-(tert-Butoxycarbonyl)-4-(2-chlorobenzyl)piperidine-4-carboxylic acid (C18H24ClNO4) is characterized by a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 1-(tert-Butoxycarbonyl)-4-(2-chlorobenzyl)piperidine-4-carboxylic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C18H24ClNO4 |
| Molecular Weight | 353.84 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related tert Standards
- 1-(Tert-butoxycarbonyl)-4-(3-chlorobenzyl)piperidine-4-carboxylic acid (CAS 1187174-08-8)
- 1-(Tert-butoxycarbonyl)-4-(4-chlorobenzyl)piperidine-4-carboxylic acid (CAS 170284-71-6)
- 2-(1-(Tert-butoxycarbonyl)-4-(4-chlorophenyl)piperidin-4-yl)acetic acid (CAS 1707367-82-5)
- 1-(tert-Butoxycarbonyl)-3-(4-chlorobenzyl)piperidine-3-carboxylicacid (CAS 174606-16-7)
- 2-[1-(tert-Butoxycarbonyl)-4-(3-chlorophenyl)piperidin-4-yl]acetic acid (CAS 644982-77-4)
- 3-((Tert-butoxycarbonyl)amino)-5-(4-chlorophenyl)thiophene-2-carboxylic acid (CAS 688763-38-4)
- 4-(((tert-Butoxycarbonyl)amino)methyl)-6-fluoro-2,2-dimethylchroman-8-carboxylic acid (CAS 1956332-03-8)
- 2-(4-(1-(tert-Butoxycarbonyl)piperidin-4-yl)-3-fluorophenoxy)acetic acid (CAS 2270906-29-9)
Recommended Standards
- (1R,2S,5S)-2-((tert-butoxycarbonyl)amino)-5-(4-chlorophenyl)cyclohexane-1-carboxylic acid (CAS 1176474-84-2)
- 2-(2-Isopropoxyphenyl)-6,8-dimethylquinoline-4-carbonyl chloride (CAS 1160263-01-3)
- tert-Butyl 4-[3-(3-chlorophenyl)ureido]piperidine-1-carboxylate (CAS 1197553-84-6)
- 6,8-Dimethyl-2-(2-propoxyphenyl)quinoline-4-carbonyl chloride (CAS 1160263-00-2)
- Tetraethyl 4,4’,4’’,4’’’-[[2,2’-Bi(1,3-dithiolylidene)]-4,4’,5,5’-tetrayl]tetrabenzoate (CAS 1356336-61-2)
- N-(4-Methoxy-6-nitrobenzo[d]thiazol-2-yl)propionamide (CAS 391222-43-8)
- Hythiemoside A (CAS 853267-91-1)
- 4,8-Bis(dodecyloxy)benzo[1,2-b:4,5-b']dithiophene (CAS 1044795-04-1)
- 2-(4-(Difluoromethyl)-3-hydroxy-6-methoxypyridin-2-yl)acetonitrile (CAS 1805546-94-4)
- Semaglutide impurity 93 (CAS CATO-C4X-222693)
- N-methyl-2-(thietan-3-ylamino)acetamide (CAS 1878054-11-5)
- N-methyl-N-(piperidin-4-ylmethyl)acetamide hydrochloride (CAS 1956331-62-6)
- Itopride Impurity 14 (CAS CATO-C4X-137714)
- Tirzepatide Impurity 13 (CAS CATO-C4X-324013)
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