3-Chloro-2-fluoro-N-methylaniline hydrochloride CAS 1187386-17-9
| CAS No. | 1187386-17-9 |
| Molecular Formula | C7H7ClFN |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 3-Chloro-2-fluoro-N-methylaniline hydrochloride is closely related to a nitrile group, fluorine/chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies 3-Chloro-2-fluoro-N-methylaniline hydrochloride (CAS 1187386-17-9), a certified reference material (molecular formula C7H7ClFNHCl, MW 196.05 g/mol) for analytical method development and quality control.
The molecular framework of 3-Chloro-2-fluoro-N-methylaniline hydrochloride (C7H7ClFNHCl) is characterized by a nitrile group, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 3-Chloro-2-fluoro-N-methylaniline hydrochloride under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C7H7ClFN HCl |
| Molecular Weight | 196.05 g/mol |
| Appearance | White to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
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- 3-(Aminomethyl)-4-fluorophenol (CAS 1243414-16-5)
- 1-Ethynyl-4-propylbenzene (CAS 62452-73-7)
- Mivacurium Chloride Impurity 22 (CAS CATO-C4X-137522)
- Semaglutide impurity 202 (CAS CATO-C4X-2226202)
Why CATO?
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