8a-(Trifluoromethyl)hexahydropyrrolo[1,2-a]pyrimidin-6(7H)-one CAS 1187570-21-3
| CAS No. | 1187570-21-3 |
| Molecular Formula | C8H11F3N2O |
| Molecular Weight | 208.18 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
8a-(Trifluoromethyl)hexahydropyrrolo[1,2-a]pyrimidin-6(7H)-one (CAS 1187570-21-3), molecular formula C8H11F3N2O and molecular weight 208.18 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to an amide group, a hydroxyl group, an ether linkage, fluorine substitution, 8a-(Trifluoromethyl)hexahydropyrrolo[1,2-a]pyrimidin-6(7H)-one is typically white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 208.18 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 8a-(Trifluoromethyl)hexahydropyrrolo[1,2-a]pyrimidin-6(7H)-one under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H11F3N2O |
| Molecular Weight | 208.18 g/mol |
| Appearance | White to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related a Standards
- alpha-(Trifluoromethyl)-1,3,5-trimethyl-1H-pyrazole-4-methanol (CAS 1250182-67-2)
- 2-[(1Z)-3-(Trifluoromethyl)cyclohexylidene]acetic acid (CAS 1344824-71-0)
- 1-Butyl-3-(trifluoromethyl)-1H-pyrazol-5-ol (CAS 143706-78-9)
- 1446786-30-6 3-(1-Methyl-5-(trifluoromethyl)-1H-pyrazol-3-yl)propan-1-ol KS-0000226C (CAS 1446786-30-6)
- 2-(Trifluoromethyl)bicyclo[2.2.1]heptane-2-carboxylic acid (CAS 1896752-94-5)
- 2-(Trifluoromethyl)spiro[3.3]Heptane-2-carboxylic acid (CAS 2166650-85-5)
- 3-(Trifluoromethyl)-1-oxa-2,8-diazaspiro[4.5]Dec-2-ene (CAS 2091398-00-2)
- 4-(trifluoromethyl)-1,3-dihydrobenzimidazol-2-one (CAS 2251-78-7)
Recommended Standards
- 1-(1-ethyl-3-methyl-1H-pyrazol-4-yl)-2,2,2-trifluoroethanol (CAS 1174851-04-7)
- 2,2-Difluoro-3-hydroxy-3-(thiophen-2-yl)propanoic acid (CAS 1204235-07-3)
- 2,2',4-Trifluoro-1,1'-biphenyl (CAS 115245-05-1)
- 5-(2,2,2-trifluoroethoxy)pyridine-3-carbonitrile (CAS 1211581-84-8)
- 1,1-Dimethoxydecane (CAS 7779-41-1)
- 2,6-Dichloro-4-iodobenzoic acid (CAS 1258298-01-9)
- (2E)-1-(2,4-Dimethylphenyl)-3-(furan-2-yl)prop-2-en-1-one (CAS 84922-00-9)
- 7-Methyl-2-phenylimidazo[1,2-a][1,3,5]triazin-4-amine (CAS 478813-62-6)
- 6-Bromo-4-chloro-2-methylbenzo[d]oxazole (CAS 1426320-94-6)
- 2-Amino-N-(((S)-2,3-dihydrobenzo[b][1,4]dioxin-2-yl)methyl)-3-methylbutanamide (CAS 1290211-41-4)
- 4-Chloro-1-(2,4-difluorophenyl)-1h-pyrazolo[3,4-d]pyrimidine (CAS 852314-02-4)
- 4-Amino-5-cyclobutyl-2,4-dihydro-3H-1,2,4-triazole-3-thione (CAS 1152587-71-7)
- 4,5-Dichloroimidazole-1-acetic Acid (CAS 474542-82-0)
- Semaglutide Impurity 128 (CAS 2490269-78-6)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com