4-Bromo-3,5-bis(4-fluorophenyl)-1H-pyrazole CAS 1187632-18-3

Description

The occurrence of 4-Bromo-3,5-bis(4-fluorophenyl)-1H-pyrazole is closely related to a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/bromine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

4-Bromo-3,5-bis(4-fluorophenyl)-1H-pyrazole (CAS 1187632-18-3) is a high-purity analytical reference standard with the molecular formula C15H9BrF2N2 and a molecular weight of 335.15 g/mol.

Owing to a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/bromine substitution, 4-Bromo-3,5-bis(4-fluorophenyl)-1H-pyrazole is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 335.15 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

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