3-Fluoro-N-methoxy-N-methylisonicotinamide CAS 1187669-49-3
| CAS No. | 1187669-49-3 |
| Molecular Formula | C8H9FN2O2 |
| Molecular Weight | 184.17 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 184.17 g/mol gives 3-Fluoro-N-methoxy-N-methylisonicotinamide distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies 3-Fluoro-N-methoxy-N-methylisonicotinamide (CAS 1187669-49-3), a certified reference material (molecular formula C8H9FN2O2, MW 184.17 g/mol) for analytical method development and quality control.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution, 3-Fluoro-N-methoxy-N-methylisonicotinamide is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 184.17 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 3-Fluoro-N-methoxy-N-methylisonicotinamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H9FN2O2 |
| Molecular Weight | 184.17 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Fluoro Standards
- (6-Fluoro-pyridin-2-yl)-carbamic Acid Ethyl Ester (CAS 1001070-25-2)
- 5-fluoro-N-methoxy-N-methylpyridine-2-carboxamide (CAS 1017598-58-1)
- 1-(5-Fluoro-2-nitrophenyl)-N-methylmethanamine (CAS 1156232-94-8)
- 2-Fluoro-5-methoxy-benzhydrazide (CAS 1167055-59-5)
- Methyl 4-fluoro-3-hydrazinylbenzoate (CAS 1206969-39-2)
- (S)-1-(2-fluoro-5-nitrophenyl)ethan-1-amine (CAS 1213009-63-2)
- (R)-1-(2-fluoro-5-nitrophenyl)ethan-1-amine (CAS 1213050-62-4)
- (R)-1-(4-Fluoro-2-nitrophenyl)ethan-1-amine (CAS 1213142-04-1)
Recommended Standards
- Ethyl 2-(5-fluoropyrimidin-2-yl)acetate (CAS 1196151-66-2)
- 2-(4-Amino-2-fluorophenoxy)acetamide (CAS 1094937-78-6)
- Ethyl 5-amino-3-fluoropicolinate (CAS 1211527-43-3)
- Methyl n-(4-amino-2-fluorophenyl)carbamate (CAS 1094107-83-1)
- 6-(3-methoxyphenyl)-3-(pyridin-3-yl)pyrazolo[1,5-a]pyrimidin-7-amine (CAS 861249-59-4)
- Chloro(2'-amino-1,1'-biphenyl-2-yl)palladium(II) dimer, min. 847616-85-7 BIS[2'-(AMINO-KAPPAN)[1,1'-BIPHENYL]-2-YL]-KAPPA;CHLORO(2'-AMINO-1,1'-BIPHENYL-2-YL)PALLADIUM(II) DIMER;DI-MU-CHLOROBIS(2'-AMINO-1,1'-BIPHENYL-2-YL-C,N)DIPALLADIUM(II);DI-MU-CHLOROBIS[2'-(AMINO-N)[1,1'-BIPHENYL]-2-YL-C]DIPALLADIUM(II);Chloro(2'-amino-1,1'-biphenyl-2-yl)palladium(II) dimer, min. SC10587 (CAS 847616-85-7)
- N’-(2-chloropropanoyl)-2-fluorobenzohydrazide (CAS 1803584-08-8)
- 2-(6-Bromo-2-chloro-3-methylphenyl)-1,3-Dioxolane (CAS 2221812-36-6)
- Methyl 4-Chloropyrrolo[2,1-f][1,2,4]triazine-6-carboxylate (CAS 1005196-61-1)
- 4-Methyl-4-phenyl-1,3-dioxane (CAS 1200-73-3)
- Sucrose Octasulfate, Ammonium Salt (CAS 74135-13-0)
- 2-((5-(4-(tert-Butyl)phenyl)-4-(4-methoxyphenyl)-4H-1,2,4-triazol-3-yl)thio)-N-(3,4-dichlorophenyl)acetamide (CAS 477313-67-0)
- 2-Chloro-N-[2-(4-methylphenoxy)butyl]aniline (CAS 1040688-71-8)
- Gastrin Tetrapeptide (CAS 1947-37-1)
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