(R)-2-Trifluoromethyl-piperazine CAS 1187928-91-1
| CAS No. | 1187928-91-1 |
| Molecular Formula | C5H9F3N2 |
| Molecular Weight | 154.13 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
(R)-2-Trifluoromethyl-piperazine (CAS 1187928-91-1) is a high-purity analytical reference standard with the molecular formula C5H9F3N2 and a molecular weight of 154.13 g/mol.
Structurally, (R)-2-Trifluoromethyl-piperazine (C5H9F3N2) contains fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 1.0, corresponding to approximately 1 ring(s) or double-bond equivalent(s). With a molecular weight of 154.13 g/mol, it falls into the medium-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), (R)-2-Trifluoromethyl-piperazine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C5H9F3N2 |
| Molecular Weight | 154.13 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 1.0 |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related R Standards
- (S)-2-(Trifluoromethyl)piperazine (CAS 1187931-35-6)
- 2-(Trifluoromethyl)piperazine (CAS 131922-05-9)
- 4-(Trifluoromethyl)pyridazine (CAS 132537-44-1)
- 3-(trifluoromethyl)cyclopentan-1-ol (CAS 1545584-15-3)
- 2-methyl-5-(trifluoromethyl)furan (CAS 17515-75-2)
- (1-(Trifluoromethyl)cyclobutyl)methanol (CAS 371917-16-7)
- (2-(Trifluoromethyl)cyclobutyl)methanol (CAS 2503204-47-3)
- [3-(trifluoromethyl)cyclobutyl]methanol (CAS 2060593-96-4)
Recommended Standards
- 2-Oxo-1,2-dihydropyrimidine-4-carbohydrazide (CAS 1148048-79-6)
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- 6,6,6-trifluorohexan-3-one (CAS 1194765-43-9)
- 4,6-Diamino-2-oxo-1,2-dihydropyrimidine-5-carbaldehyde (CAS 113203-37-5)
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- 2,2-Bis[4-(3-aminophenoxy)pheny]propane (CAS 87880-61-3)
- Benzyl ((1-((S)-2-aminopropanoyl)piperidin-2-yl)methyl)(isopropyl)carbamate (CAS 1354024-16-0)
- 2-((1-(2-Oxo-2-(pyrrolidin-1-yl)ethyl)-1H-indol-3-yl)thio)acetonitrile (CAS 895799-88-9)
- 862SGU1BRL 216863-66-0 L 756423 D-erythro-Pentonamide, 5-((2S)-4-(2-benzofuranylmethyl)-2-(((1,1-dimethylethyl)amino)carbonyl)-1-piperazinyl)-2,3,5-trideoxy-N-((1S,2R)-2,3-dihydro-2-hydroxy-1H-inden-1-yl)-2-(phenylmethyl)- MK 944a L-756423 N-(2(R)-hydroxy-1(S)-indanyl)-2(R)-phenylmethyl-4(S)-hydroxy-5-(1-(4-(2-benzo(b)furanylmethyl)-2(S)-N'-(tert-butylcarboxamido)piperazinyl))pentanamide UNII-862SGU1BRL (CAS 216863-66-0)
- trans-4-[4-(Cyclopropylmethyl)piperazin-1-yl]cyclohexanamine (CAS 876461-31-3)
- n-(5-Amino-2-fluorophenyl)thiophene-2-sulfonamide (CAS 926242-51-5)
- Semaglutide Impurity 166 (CAS 1395881-03-4)
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