2-Chloro-5,6,8-trifluoroquinoline CAS 1188002-18-7
| CAS No. | 1188002-18-7 |
| Molecular Formula | C9H3ClF3N |
| Molecular Weight | 217.58 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 2-Chloro-5,6,8-trifluoroquinoline is closely related to a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
2-Chloro-5,6,8-trifluoroquinoline (CAS 1188002-18-7), molecular formula C9H3ClF3N and molecular weight 217.58 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, 2-Chloro-5,6,8-trifluoroquinoline (C9H3ClF3N) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 7.0, corresponding to approximately 7 ring(s) or double-bond equivalent(s). With a molecular weight of 217.58 g/mol, it falls into the medium-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 2-Chloro-5,6,8-trifluoroquinoline meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C9H3ClF3N |
| Molecular Weight | 217.58 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related Chloro Standards
- 4-Chloro-6,7,8-trifluoroquinoline (CAS 1020087-33-5)
- 1-(2-Chloro-4-fluoro-5-nitrophenyl)ethanone (CAS 110322-88-8)
- 1-(4-Chloro-2-fluoro-5-nitrophenyl)ethanone (CAS 1292836-16-8)
- 1-(2-Chloro-5-fluoro-4-nitrophenyl)ethanone (CAS 149903-96-8)
- 2-chloro-1-(2-fluoro-4-nitrophenyl)ethan-1-one (CAS 1539494-36-4)
- [(4-chloro-3-fluorophenyl)carbamoyl]formic acid (CAS 480451-91-0)
- Methyl 2-chloro-5-fluoro-6-formylnicotinate (CAS 2750929-50-9)
- 5-Chloro-2,4-dinitroaniline (CAS 3013-86-3)
Recommended Standards
- 6-Chloro-2,4-Dinitroaniline (CAS 3531-19-9)
- Methyl 6-chloro-3-nitropyrazine-2-carboxylate (CAS 89690-75-5)
- 2-Fluoro-4-methyl-6-nitrobenzoyl chloride (CAS 1806306-40-0)
- 2-Fluoro-4-methyl-5-nitrobenzoyl chloride (CAS 1806427-38-2)
- (2,4-Dimethylcyclohex-3-en-1-yl)methyl acetate (CAS 67634-26-8)
- 1,2-Phenylenebis[diphenyl]phosphine iron complex (CAS 101566-80-7)
- 4-ethylcyclohexanecarbaldehyde (CAS 1246443-71-9)
- Ethyl isopropyl sulfone (CAS 4853-75-2)
- (3-Chlorophenyl)(pyrrolidin-1-yl)methanone (CAS 329058-19-7)
- 2-(1-Ethyl-5-fluoro-3-methyl-1H-pyrazol-4-yl)acetic acid (CAS 1823818-15-0)
- 3-(1H-Benzo[d]imidazol-2-yl)-6-chloro-4H-chromen-4-one (CAS 293740-39-3)
- Cefdinir Impurity 39 (CAS 104797-47-9)
- 2-(4-Ethoxybenzyl)-5-hydroxypyrimidin-4(1H)-one (CAS 55342-68-2)
- Fibrinopeptide A, human TFA (CAS 61533-47-9)
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