6-Fluoro-2-(trifluoromethyl)benzo[d]thiazole CAS 1188026-75-6
| CAS No. | 1188026-75-6 |
| Molecular Formula | C8H3F4NS |
| Molecular Weight | 221.17 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 6-Fluoro-2-(trifluoromethyl)benzo[d]thiazole is closely related to a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
6-Fluoro-2-(trifluoromethyl)benzo[d]thiazole (CAS 1188026-75-6), molecular formula C8H3F4NS and molecular weight 221.17 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 6-Fluoro-2-(trifluoromethyl)benzo[d]thiazole (C8H3F4NS) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H3F4NS |
| Molecular Weight | 221.17 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
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Recommended Standards
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- 5-Chloro-2,2-difluoro-6-nitrobenzo[d][1,3]dioxole (CAS 1027513-83-2)
- 3'-Bromo-5'H,7'H-spiro[cyclopropane-1,6'-pyrazolo[5,1-b][1,3]oxazine] (CAS 1785105-75-0)
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- Semaglutide impurity 29 (CAS CATO-C4X-222629)
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