4-(2-Fluorophenyl)-2-methylthiazole-5-carboxylic acid CAS 1188184-08-8

Description

4-(2-Fluorophenyl)-2-methylthiazole-5-carboxylic acid (CAS 1188184-08-8), molecular formula C11H8FNO2S and molecular weight 237.25 g/mol, is a CATO reference standard with documented purity and traceability.

Structurally, 4-(2-Fluorophenyl)-2-methylthiazole-5-carboxylic acid (C11H8FNO2S) contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 8.0, corresponding to approximately 8 ring(s) or double-bond equivalent(s). With a molecular weight of 237.25 g/mol, it falls into the medium-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

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