2-(2-Bromophenyl)-4,6-dichloropyrimidine CAS 1188237-02-6
| CAS No. | 1188237-02-6 |
| Molecular Formula | C10H5BrCl2N2 |
| Molecular Weight | 303.97 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
2-(2-Bromophenyl)-4,6-dichloropyrimidine (CAS 1188237-02-6), molecular formula C10H5BrCl2N2 and molecular weight 303.97 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 2-(2-Bromophenyl)-4,6-dichloropyrimidine (C10H5BrCl2N2) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine/bromine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 2-(2-Bromophenyl)-4,6-dichloropyrimidine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H5BrCl2N2 |
| Molecular Weight | 303.97 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | Cl/Br-containing |
| Nitrogen Atoms | 2 |
Related Bromophenyl Standards
- 2-(3-Bromophenyl)-4,6-dichloropyrimidine (CAS 1188237-09-3)
- 5-(4-Bromophenyl)-4,6-dichloropyrimidine (CAS 146533-41-7)
- 4-(4-Bromophenyl)-2,6-dichloropyrimidine (CAS 1490189-81-5)
- 4-(2-Bromophenyl)-2,6-dichloropyrimidine (CAS 1493045-03-6)
- 5-(2-Bromophenyl)-4,6-dichloropyrimidine (CAS 1516860-25-5)
- 5-(3-Bromophenyl)-4,6-dichloropyrimidine (CAS 1532412-37-5)
- 2-(4-Bromophenyl)-4,6-dichloropyrimidine (CAS 83217-26-9)
- N-(2-Bromophenyl)-1,1,1-trifluoromethanesulfonamide (CAS 23384-07-8)
Recommended Standards
- 3-bromo-6-iodo-2-methyl-pyridine (CAS 1008361-77-0)
- 4,5-Dibromo-2,3-difluorothiophenol (CAS 1806351-46-1)
- 2,6-Dibromo-3,4-difluorothiophenol (CAS 1806351-34-7)
- 2,3-Dibromo-4,6-difluorothiophenol (CAS 1806351-24-5)
- N-(4-chlorophenyl)-N-methyl-3-(trifluoromethyl)benzamide (CAS 860649-45-2)
- Strontium Acetate Hemihydrate (CAS 14692-29-6)
- 3,6-Dicyclopropylisoxazolo[5,4-b]pyridine-4-carboxylic acid (CAS 937600-24-3)
- 7-Bromo-1,3-dihydrofuro[3,4-c]pyridin-4-amine (CAS 1902982-92-6)
- 1-Amino-3-(3-chloropyridin-4-yl)propan-2-ol (CAS 1487549-56-3)
- [(3-Isopropyl-4,5-dihydro-5-isoxazolyl)methyl]amine hydrochloride (CAS 1609407-96-6)
- Salbutamol EP Impurity N (R-Isomer) (CAS CATO-C4X-1176200)
- tert-butyl 2-methylpent-4-enoate (CAS 93958-20-4)
- 4-(Trifluoromethyl)pyridine-3-acetonitrile (CAS 1227514-93-3)
- Gastric Inhibitory Polypeptide (3-42) (human) trifluoroacetate salt (CAS 1802086-25-4)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com