1-(4-fluorophenyl)-3-(trifluoromethyl)-1H-pyrazol-5-amine CAS 1188909-71-8
| CAS No. | 1188909-71-8 |
| Molecular Formula | C10H7F4N3 |
| Molecular Weight | 245.18 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 1-(4-fluorophenyl)-3-(trifluoromethyl)-1H-pyrazol-5-amine (CAS 1188909-71-8), a certified reference material (molecular formula C10H7F4N3, MW 245.18 g/mol) for analytical method development and quality control.
The molecular framework of 1-(4-fluorophenyl)-3-(trifluoromethyl)-1H-pyrazol-5-amine (C10H7F4N3) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 1-(4-fluorophenyl)-3-(trifluoromethyl)-1H-pyrazol-5-amine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H7F4N3 |
| Molecular Weight | 245.18 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related fluorophenyl Standards
- 4-(4-Fluorophenyl)-3-(trifluoromethyl)-1h-pyrazol-5-amine (CAS 1046046-44-9)
- 2-(4-(3-Fluorophenyl)-2,3-dioxo-3,4-dihydropyrazin-1(2H)-yl)acetonitrile (CAS 1226443-09-9)
- 2-((4-Fluorophenyl)amino)-1H-purin-6(7H)-one (CAS 131933-80-7)
- (4-Fluorophenyl)(3-nitrophenyl)methanone (CAS 16574-53-1)
- (2-Fluorophenyl)(2-nitrophenyl)methanone (CAS 30682-54-3)
- (2-Fluorophenyl)(3-nitrophenyl)methanone (CAS 890098-20-1)
- (3-Fluorophenyl)(3-nitrophenyl)methanone (CAS 890098-21-2)
- (4-Fluorophenyl)(4-nitrophenyl)methanone (CAS 2195-47-3)
Recommended Standards
- 1-Bromo-3-isobutylthiobenzene (CAS 1199773-06-2)
- 3-Amino-5-[4-fluoro-3-(trifluoromethyl)phenyl]pyrazole (CAS 1040724-42-2)
- 1-Bromo-4-butylthiobenzene (CAS 121392-35-6)
- 3-Fluoro-4-(3-(trifluoromethyl)-1H-pyrazol-1-yl)aniline (CAS 1006468-65-0)
- TEGDN (CAS 111-22-8)
- Potassium trifluoro(4-fluorobenzoyl)borate (CAS 1590389-14-2)
- 3-(2-Oxo-3-phenyl-1,2-dihydroquinolin-6-yl)propanoic acid (CAS 1082390-77-9)
- 2,4,6-Tris(dimethylaminomethyl)phenol (CAS 90-72-2)
- (5-(Difluoromethyl)pyridin-2-yl)methanamine oxalate (CAS 2411641-51-3)
- 4-Ethyl-2-methyl-1H-pyrrole (CAS 5690-96-0)
- (2R,3S,5R)-2-((Bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(5-methyl-2-oxo-4-((2-(6-(2,2,2-trifluoroacetamido)hexanamido)ethyl)amino)pyrimidin-1(2H)-yl)tetrahydrofuran-3-yl methyl diisopropylphosphoramidate (CAS 117032-52-7)
- 7-Methyl-3-(trimethylsilyl)-1H-indazole (CAS 679795-02-9)
- 3-Fluoro-2-hydroxybenzonitrile (CAS 28177-74-4)
- Semaglutide impurity 289 (CAS CATO-C4X-2226289)
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