4-Bromo-6-(trifluoromethoxy)quinoline CAS 1189105-68-7
| CAS No. | 1189105-68-7 |
| Molecular Formula | C10H5BrF3NO |
| Molecular Weight | 292.05 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO supplies 4-Bromo-6-(trifluoromethoxy)quinoline (CAS 1189105-68-7), a certified reference material (molecular formula C10H5BrF3NO, MW 292.05 g/mol) for analytical method development and quality control.
Structurally, 4-Bromo-6-(trifluoromethoxy)quinoline (C10H5BrF3NO) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/bromine substitution. The molecule exhibits a degree of unsaturation (DBE) of 7.0, corresponding to approximately 7 ring(s) or double-bond equivalent(s). With a molecular weight of 292.05 g/mol, it falls into the medium-molecular-weight range. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
As a certified reference material (CRM), 4-Bromo-6-(trifluoromethoxy)quinoline meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H5BrF3NO |
| Molecular Weight | 292.05 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | F/Br-containing |
| Nitrogen Atoms | 1 |
Related Bromo Standards
- 8-Bromo-6-(trifluoromethoxy)quinoline (CAS 1020253-25-1)
- 3-Bromo-6-(trifluoromethoxy)quinoline (CAS 1059064-17-3)
- 5-Bromo-8-(trifluoromethoxy)quinoline (CAS 1065074-23-8)
- 5-Bromo-8-(trifluoromethyl)quinolin-4(1H)-one (CAS 1065092-40-1)
- 8-Bromo-5-(trifluoromethyl)quinolin-4(1H)-one (CAS 1065092-42-3)
- 8-Bromo-6-(trifluoromethyl)quinolin-4(1H)-one (CAS 1065092-51-4)
- 6-Bromo-8-(trifluoromethyl)quinolin-4(1H)-one (CAS 1065092-55-8)
- 8-Bromo-5-(trifluoromethoxy)quinoline (CAS 1133115-91-9)
Recommended Standards
- 4-Bromo-8-(trifluoromethoxy)quinoline (CAS 1189105-60-9)
- 4-Bromo-6-(trifluoromethyl)-1(2H)-isoquinolinone (CAS 1227608-00-5)
- 4-Bromo-7-(trifluoromethoxy)quinoline (CAS 1189105-57-4)
- 1-(4-Bromo-3-indolyl)-2,2,2-trifluoroethanone (CAS 1253929-39-3)
- 1-{[4-(trifluoromethoxy)phenyl]methyl}-1H-pyrazole-4-carbaldehyde (CAS 1481183-82-7)
- [(4-Methylphenyl)methyl]({[(4-methylphenyl)methyl]sulfamoyl})amine (CAS 250165-80-1)
- N1-(tert-Butyl)-N2-(2-(1-methyl-1H-pyrrol-2-yl)-2-morpholinoethyl)oxalamide (CAS 1049398-80-2)
- 2-(2-Bromoethoxy)-1,1,1-trifluoroethane (CAS 133068-36-7)
- 4-(Chloromethyl)pyridine-2-carbonitrile (CAS 71935-33-6)
- Methyl 3-(N-((4-methyl-6-oxo-1,6-dihydro-1,3,5-triazin-2-yl)carbamoyl)sulfamoyl)thiophene-2-carboxylate (CAS 150258-68-7)
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