4-Chloro-2-phenyl-8-(trifluoromethyl)quinoline CAS 1189105-84-7
| CAS No. | 1189105-84-7 |
| Molecular Formula | C16H9ClF3N |
| Molecular Weight | 307.70 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 4-Chloro-2-phenyl-8-(trifluoromethyl)quinoline meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
4-Chloro-2-phenyl-8-(trifluoromethyl)quinoline (CAS 1189105-84-7), molecular formula C16H9ClF3N and molecular weight 307.70 g/mol, is a CATO reference standard with documented purity and traceability.
4-Chloro-2-phenyl-8-(trifluoromethyl)quinoline (C16H9ClF3N) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C16H9ClF3N |
| Molecular Weight | 307.70 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related Chloro Standards
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- N-ethyl-3-phenylprop-2-yn-1-amine (CAS 18158-60-6)
- Peptide 46 (H-4054.0500) (CAS 192122-40-0)
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