4-Bromo-5,8-difluoro-2-phenylquinoline CAS 1189107-68-3

Purity 97%+In StockPharmaceutical Standards
CAS No.1189107-68-3
Molecular FormulaC15H8BrF2N
Molecular Weight320.13 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

4-Bromo-5,8-difluoro-2-phenylquinoline CAS 1189107-68-3 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 4-Bromo-5,8-difluoro-2-phenylquinoline.

CATO supplies 4-Bromo-5,8-difluoro-2-phenylquinoline (CAS 1189107-68-3), a certified reference material (molecular formula C15H8BrF2N, MW 320.13 g/mol) for analytical method development and quality control.

The molecular framework of 4-Bromo-5,8-difluoro-2-phenylquinoline (C15H8BrF2N) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/bromine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

CATO manufactures 4-Bromo-5,8-difluoro-2-phenylquinoline under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC15H8BrF2N
Molecular Weight320.13 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)11.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1989
Halogen ContentF/Br-containing
Nitrogen Atoms1

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