3-(4-Aminopiperidin-1-yl)-1-(6-chloropyridin-3-yl)propan-1-one hydrochloride CAS 1189431-89-7

Purity 97%+In StockPharmaceutical Standards
CAS No.1189431-89-7
Molecular FormulaC13H18ClN3O
Molecular WeightN/A
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

3-(4-Aminopiperidin-1-yl)-1-(6-chloropyridin-3-yl)propan-1-one hydrochloride CAS 1189431-89-7 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 3-(4-Aminopiperidin-1-yl)-1-(6-chloropyridin-3-yl)propan-1-one hydrochloride.

3-(4-Aminopiperidin-1-yl)-1-(6-chloropyridin-3-yl)propan-1-one hydrochloride (CAS 1189431-89-7), molecular formula C13H18ClN3OHCl and molecular weight 304.22 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of 3-(4-Aminopiperidin-1-yl)-1-(6-chloropyridin-3-yl)propan-1-one hydrochloride (C13H18ClN3OHCl) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 3-(4-Aminopiperidin-1-yl)-1-(6-chloropyridin-3-yl)propan-1-one hydrochloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC13H18ClN3O HCl
Molecular Weight304.22 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)5.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1989
Halogen ContentCl-containing
Nitrogen Atoms3

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