3-(6-Chloro-[1,2,4]triazolo[4,3-b]pyridazin-3-yl)-1-(pyrrolidin-1-yl)propan-1-one CAS 1189749-77-6
| CAS No. | 1189749-77-6 |
| Molecular Formula | C12H14ClN5O |
| Molecular Weight | 279.73 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
3-(6-Chloro-[1,2,4]triazolo[4,3-b]pyridazin-3-yl)-1-(pyrrolidin-1-yl)propan-1-one (CAS 1189749-77-6), molecular formula C12H14ClN5O and molecular weight 279.73 g/mol, is a CATO reference standard with documented purity and traceability.
3-(6-Chloro-[1,2,4]triazolo[4,3-b]pyridazin-3-yl)-1-(pyrrolidin-1-yl)propan-1-one (C12H14ClN5O) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 3-(6-Chloro-[1,2,4]triazolo[4,3-b]pyridazin-3-yl)-1-(pyrrolidin-1-yl)propan-1-one under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C12H14ClN5O |
| Molecular Weight | 279.73 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 5 |
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Recommended Standards
- 6-(Chloromethyl)-N2-(4-ethoxyphenyl)-1,3,5-triazine-2,4-diamine (CAS 105704-31-2)
- N-(3-(1H-1,2,4-Triazol-1-yl)propyl)-2-amino-5-chlorobenzamide (CAS 103447-60-5)
- Cyprofuram (CAS 69581-33-5)
- 6-(Chloromethyl)-N2-(2-ethoxyphenyl)-1,3,5-triazine-2,4-diamine (CAS 1379811-41-2)
- 8-Methyl-2,8-diazaspiro[4.5]decane dihydrochloride (CAS 1489508-12-4)
- [(2,4-Dimethoxyphenyl)methyl](2-methylpropyl)amine (CAS 135701-58-5)
- 4-Acetylphenethyl pyrimidine-5-carboxylate (CAS 62328-07-8)
- 4-Aminoindole (CAS 5192-23-4)
- Forestine (CAS 91794-14-8)
- 2,2-Dimethylhexan-3-one (CAS 5405-79-8)
- 4,6-Dihydro-1H-[1,2]dithiino[4,5-c]pyrrole (CAS 173731-42-5)
- 2,6-Dioxo-1-phenyl-1,2,3,6-tetrahydropyrimidine-4-carboxylic acid (CAS 723-76-2)
- 1-((2-Ethoxy-4,5-dimethylphenyl)sulfonyl)azepane (CAS 898646-78-1)
- Myristoyl Pentapeptide -4 acetate (CAS 959610-30-1(free base))
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