4-(3,3,3-Trifluoropropoxy)benzoic acid CAS 1190044-69-9
| CAS No. | 1190044-69-9 |
| Molecular Formula | C10H9F3O3 |
| Molecular Weight | 234.17 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 4-(3,3,3-Trifluoropropoxy)benzoic acid.
CATO supplies 4-(3,3,3-Trifluoropropoxy)benzoic acid (CAS 1190044-69-9), a certified reference material (molecular formula C10H9F3O3, MW 234.17 g/mol) for analytical method development and quality control.
The molecular framework of 4-(3,3,3-Trifluoropropoxy)benzoic acid (C10H9F3O3) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H9F3O3 |
| Molecular Weight | 234.17 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | F-containing |
Related Trifluoropropoxy Standards
- 3-(3,3,3-Trifluoropropoxy)benzoic acid (CAS 1477900-96-1)
- 6-(3,3,3-Trifluoropropoxy)nicotinic acid (CAS 1072855-39-0)
- 6-(3,3,3-TRIFLUOROPROPOXY)-2,3-DIHYDRO-1H-INDEN-1-ONE (CAS 1383985-21-4)
- 1-Methyl-5-[(3,3,3-trifluoropropoxy)methyl]-1h-pyrazol-3-amine (CAS 1328640-70-5)
- N-(4-(3,3,3-trifluoropropoxy)benzyl)ethanamine (CAS 1465524-59-7)
- N-(2-(3,3,3-trifluoropropoxy)benzyl)ethanamine (CAS 1491618-31-5)
- [4-(3,3,3-trifluoropropoxy)phenyl]methanol (CAS 1340442-62-7)
- (3-(3,3,3-Trifluoropropoxy)phenyl)methanol (CAS 1341968-92-0)
Recommended Standards
- Methyl 3-(2,2,2-trifluoro-1-hydroxyethyl)benzoate (CAS 1188323-28-5)
- 2-[2-(trifluoromethyl)phenoxy]propanoic acid (CAS 119411-77-7)
- 8-Nitro-[1,3]dioxolo[4,5-g]isoquinolin-7(6H)-one (CAS 113982-74-4)
- 2-Hydroxy-3-(4-(trifluoromethyl)phenyl)propanoic acid (CAS 1207255-93-3)
- 4-Chloro-3-nitro-N-propylbenzamide (CAS 321531-57-1)
- N-(4-iodo-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)pivalamide (CAS 2390149-54-7)
- piperazine-1-carboxamide;hydrochloride (CAS 474711-89-2)
- 2-(3-Methoxypropoxy)-N-methyl-1-ethanamine (CAS 883545-98-0)
- (6-Ethylpyridin-2-yl)methanamine (CAS 83004-19-7)
- 2-((4-(4-Bromophenyl)-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl)thio)-N-(3-chlorophenyl)acetamide (CAS 477331-19-4)
- (2-Cyclohexylthiazol-5-yl)methanol (CAS 1267424-35-0)
- 60414-59-7 2(1H)-Pyrimidinethione, 4-phenyl- 2-Mercapto-4-phenylpyrimidine 4-Phenyl-2(1H)-pyrimidinethione (CAS 60414-59-7)
- 2-(1H-Benzo[d]imidazol-2-yl)-5-bromophenol (CAS 402929-34-4)
- Semaglutide impurity 54 (CAS CATO-C4X-222654)
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