6-Fluoro-1H-pyrrolo[2,3-b]pyridine-3-carbaldehyde CAS 1190314-77-2
| CAS No. | 1190314-77-2 |
| Molecular Formula | C8H5FN2O |
| Molecular Weight | 164.14 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
6-Fluoro-1H-pyrrolo[2,3-b]pyridine-3-carbaldehyde (CAS 1190314-77-2), molecular formula C8H5FN2O and molecular weight 164.14 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 6-Fluoro-1H-pyrrolo[2,3-b]pyridine-3-carbaldehyde (C8H5FN2O) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO manufactures 6-Fluoro-1H-pyrrolo[2,3-b]pyridine-3-carbaldehyde under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H5FN2O |
| Molecular Weight | 164.14 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Fluoro Standards
- 5-fluoro-1H-indazole-7-carbaldehyde (CAS 1100214-39-8)
- 7-Fluoro-1H-indazole-4-carbaldehyde (CAS 1186334-92-8)
- 6-Fluoro-1H-pyrrolo[2,3-b]pyridine-4-carbaldehyde (CAS 1190310-04-3)
- 7-Fluoro-1H-pyrrolo[3,2-c]pyridine-3-carbaldehyde (CAS 1190315-32-2)
- 6-Fluoro-1h-pyrrolo[3,2-b]pyridine-3-carbaldehyde (CAS 1190316-09-6)
- 4-Fluoro-1H-pyrrolo[2,3-c]pyridine-3-carbaldehyde (CAS 1190320-43-4)
- 7-Fluoro-1H-pyrrolo[2,3-c]pyridine-3-carbaldehyde (CAS 1190321-14-2)
- 5-Fluoro-1H-pyrrolo[3,2-b]pyridine-3-carbaldehyde (CAS 1190322-05-4)
Recommended Standards
- 7-Fluorocinnolin-4(1H)-one (CAS 1176417-30-3)
- 4-Cyano-2-fluorobenzamide (CAS 1046447-03-3)
- 8-fluoroimidazo[1,2-a]pyridine-2-carbaldehyde (CAS 1020033-80-0)
- 7-Fluoro-4H-pyrido[1,2-a]pyrimidin-4-one (CAS 1198413-01-2)
- 5-(morpholin-4-yl)-4-phenyl-4H-1,2,4-triazole-3-thiol (CAS 94971-19-4)
- (1S)-1-(1,3-thiazol-2-yl)propan-1-amine (CAS 1220123-43-2)
- 4-(tert-Butyl)-3-cyclopropoxy-5-methylpyridine (CAS 1243329-27-2)
- Ethyl 2-oxo-1,2,3,4-tetrahydroquinoline-7-carboxylate (CAS 697306-33-5)
- 1-Chloro-1-(3-(trifluoromethyl)phenyl)propan-2-one (CAS 97132-58-6)
- Ethyl 6-acetyl-2-oxo-1,2-dihydropyrimidine-5-carboxylate (CAS 62327-96-2)
- Glaziovine (CAS 6808-72-6)
- 3-(M-tolyloxy)pyrrolidine (CAS 1185051-04-0)
- (S)-1-(3,4-Dimethylphenyl)propan-1-amine hydrochloride (CAS 1777812-71-1)
- Insulin Detemir (CAS 169148-63-4)
Why CATO?
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