5-Fluoro-1H-pyrrolo[2,3-b]pyridin-3-amine CAS 1190321-56-2
| CAS No. | 1190321-56-2 |
| Molecular Formula | C7H6FN3 |
| Molecular Weight | 151.14 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 5-Fluoro-1H-pyrrolo[2,3-b]pyridin-3-amine (C7H6FN3) is characterized by a nitrile group, fluorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
5-Fluoro-1H-pyrrolo[2,3-b]pyridin-3-amine (CAS 1190321-56-2), molecular formula C7H6FN3 and molecular weight 151.14 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 5-Fluoro-1H-pyrrolo[2,3-b]pyridin-3-amine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C7H6FN3 |
| Molecular Weight | 151.14 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
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- 6-Fluoro-1H-pyrrolo[2,3-b]pyridin-4-amine (CAS 1190309-99-9)
Recommended Standards
- 6-Fluoro-1H-pyrrolo[2,3-b]pyridin-3-amine (CAS 1190321-50-6)
- 7-Fluoro-1H-pyrrolo[2,3-c]pyridin-3-amine (CAS 1190322-29-2)
- 6-Fluoro-1H-pyrrolo[3,2-b]pyridin-3-amine (CAS 1190319-66-4)
- 6-Amino-4-fluoro-7-azaindole (CAS 1190322-89-4)
- (R)-1-Benzyl-3-bromopiperidine (CAS 1353997-04-2)
- 7-Chloro-4-((3-(trifluoromethyl)benzyl)thio)-2,3-dihydrobenzo[b][1,4]thiazepine (CAS 477855-80-4)
- 2,4-Di(aziridin-1-yl)-6-chloropyrimidine (CAS 2482-80-6)
- E 3330 (CAS 136164-66-4)
- 3,3,5,5-tetramethyl-1-(pyridin-2-yl)cyclohexan-1-ol (CAS 2128280-37-3)
- Pemafibrate Impurity 44 (CAS CATO-C4X-290344)
- 2-Bromo-9,9-dibutylfluorene (CAS 88223-35-2)
- 2-Oxo-1-(prop-2-en-1-yl)-5-[3-(trifluoromethyl)phenyl]-1,2-dihydropyridine-3-carbonitrile (CAS 338964-43-5)
- 2,3-Dimethoxy-11-(3-(trifluoromethyl)phenyl)-5,11,12,12a-tetrahydropyrazolo[3',4':4,5]pyrido[2,1-a]isoquinolin-8(6H)-one (CAS 685107-27-1)
- Semaglutide impurity 66 (CAS CATO-C4X-222666)
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