3-Amino-1H-pyrrolo[2,3-c]pyridine-4-carbonitrile CAS 1190322-35-0
| CAS No. | 1190322-35-0 |
| Molecular Formula | C8H6N4 |
| Molecular Weight | 158.16 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 3-Amino-1H-pyrrolo[2,3-c]pyridine-4-carbonitrile (C8H6N4) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
3-Amino-1H-pyrrolo[2,3-c]pyridine-4-carbonitrile (CAS 1190322-35-0) is a high-purity analytical reference standard with the molecular formula C8H6N4 and a molecular weight of 158.16 g/mol.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 3-Amino-1H-pyrrolo[2,3-c]pyridine-4-carbonitrile meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H6N4 |
| Molecular Weight | 158.16 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Nitrogen Atoms | 4 |
Related Amino Standards
- 3-Amino-1H-pyrrolo[2,3-b]pyridine-4-carbonitrile (CAS 1000340-50-0)
- 3-Amino-1H-indazole-7-carbonitrile (CAS 1137451-25-2)
- 1-Amino-1H-indazole-3-carbonitrile (CAS 116589-59-4)
- 5-Amino-1H-indazole-4-carbonitrile (CAS 1167056-70-3)
- 3-Amino-1H-pyrrolo[3,2-b]pyridine-5-carbonitrile (CAS 1190311-61-5)
- 3-Amino-1H-pyrrolo[3,2-b]pyridine-6-carbonitrile (CAS 1190312-49-2)
- 3-Amino-1H-pyrrolo[2,3-c]pyridine-7-carbonitrile (CAS 1190318-78-5)
- 3-Amino-1H-pyrrolo[3,2-b]pyridine-7-carbonitrile (CAS 1190319-38-0)
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