3-Chloro-1H-pyrrolo[3,2-b]pyridine-6-carboxylic acid CAS 1190322-95-2
| CAS No. | 1190322-95-2 |
| Molecular Formula | C8H5ClN2O2 |
| Molecular Weight | 196.59 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 3-Chloro-1H-pyrrolo[3,2-b]pyridine-6-carboxylic acid (C8H5ClN2O2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
CATO supplies 3-Chloro-1H-pyrrolo[3,2-b]pyridine-6-carboxylic acid (CAS 1190322-95-2), a certified reference material (molecular formula C8H5ClN2O2, MW 196.59 g/mol) for analytical method development and quality control.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H5ClN2O2 |
| Molecular Weight | 196.59 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Chloro Standards
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Recommended Standards
- 3-Chloro-1H-pyrrolo[2,3-c]pyridine-4-carboxylic acid (CAS 1190320-29-6)
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- 4-Chloro-1H-pyrrolo[3,2-c]pyridine-3-carboxylic acid (CAS 1190316-39-2)
- 2-Chlorobenzo[d]oxazole-5-carboxamide (CAS 1198793-47-3)
- 4-methoxypyridine-2-carboxylic acid hydrochloride (CAS 123811-74-5)
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- (S)-Tetrahydrofuran-3-yl (3-((phenoxycarbonyl)amino)benzyl)carbamate (CAS 914810-54-1)
- 3-Amino-2-oxo-3,4-dihydroquinolin-1(2H)-yl dimethylcarbamate hydrochloride (CAS 1258545-29-7)
- Ganirelix 1-4 peptide (CAS 208599-57-9)
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