1-(Tetrahydro-2H-pyran-4-yl)-1H-pyrazol-4-amine CAS 1190380-49-4

Purity 97%+In StockPharmaceutical Standards
CAS No.1190380-49-4
Molecular FormulaC8H13N3O
Molecular Weight167.21 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

1-(Tetrahydro-2H-pyran-4-yl)-1H-pyrazol-4-amine CAS 1190380-49-4 chemical structure

Description

The molecular framework of 1-(Tetrahydro-2H-pyran-4-yl)-1H-pyrazol-4-amine (C8H13N3O) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

1-(Tetrahydro-2H-pyran-4-yl)-1H-pyrazol-4-amine (CAS 1190380-49-4) is a high-purity analytical reference standard with the molecular formula C8H13N3O and a molecular weight of 167.21 g/mol.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 1-(Tetrahydro-2H-pyran-4-yl)-1H-pyrazol-4-amine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC8H13N3O
Molecular Weight167.21 g/mol
AppearanceOff-white to pale yellow crystalline powder. (faint amine-like odor)
Purity97%+
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityLight-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)4.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1989
Nitrogen Atoms3

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