5-Fluoro-N-methylisoindolin-2-amine hydrochloride CAS 1190890-20-0
| CAS No. | 1190890-20-0 |
| Molecular Formula | C9H11FN2 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO supplies 5-Fluoro-N-methylisoindolin-2-amine hydrochloride (CAS 1190890-20-0), a certified reference material (molecular formula C9H11FN2HCl, MW 202.66 g/mol) for analytical method development and quality control.
The molecular framework of 5-Fluoro-N-methylisoindolin-2-amine hydrochloride (C9H11FN2HCl) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
As a certified reference material (CRM), 5-Fluoro-N-methylisoindolin-2-amine hydrochloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C9H11FN2 HCl |
| Molecular Weight | 202.66 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
Related Fluoro Standards
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- 3-Fluoro-2-nitrobenzoic Acid (CAS 1000339-51-4)
Recommended Standards
- tert-Butyl 2-oxa-5-azabicyclo[2.2.1]heptane-5-carboxylate (CAS 127708-09-2)
- 2-(1-(2-Methoxyphenyl)cyclopropyl)acetic acid (CAS 1225528-06-2)
- (2-(Dimethyl(4-(methylthio)phenyl)silyl)phenyl)methanol (CAS 1217863-50-7)
- 4-Ethyl-2-methylthiophen-3-amine (CAS 87675-31-8)
- 5-(Trifluoromethyl)imidazo[1,2-a]pyridin-3-amine (CAS 1780806-70-3)
- 1-Oxo-1-[5-(2-pyridyl)oxazol-2-yl]-7-phenylheptane (CAS 681135-77-3)
- 4-[(4-Benzylphenoxy)methyl]piperidinehydrochloride (CAS 1093653-13-4)
- 2-(Difluoromethyl)-5-(methylthio)benzo[d]oxazole (CAS 1806322-56-4)
- (S)-1-(5-Chloropyridin-2-yl)ethanol (CAS 1016227-95-4)
- endo-Ser39-Tirzepatide (CAS CATO-CPTD788935)
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