PHT-427, 98%, an inhibitor of the pleckstrin homology (PH) domain of Akt CAS 1191951-57-1

Purity 97%+In StockPharmaceutical Standards
CAS No.1191951-57-1
Molecular FormulaC20H31N3O2S2
Molecular Weight409.61 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

PHT-427, 98%, an inhibitor of the pleckstrin homology (PH) domain of Akt CAS 1191951-57-1 chemical structure

Description

The occurrence of PHT-427, 98%, an inhibitor of the pleckstrin homology (PH) domain of Akt is closely related to a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

PHT-427, 98%, an inhibitor of the pleckstrin homology (PH) domain of Akt (CAS 1191951-57-1), molecular formula C20H31N3O2S2 and molecular weight 409.61 g/mol, is a CATO reference standard with documented purity and traceability.

Owing to a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, PHT-427, 98%, an inhibitor of the pleckstrin homology (PH) domain of Akt is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 409.61 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), PHT-427, 98%, an inhibitor of the pleckstrin homology (PH) domain of Akt meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC20H31N3O2S2
Molecular Weight409.61 g/mol
Purity97%+
StorageStore in a cool place (≤25°C), protect from light, keep sealed and dry
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening
Degree of Unsaturation (DBE)7.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1989
Nitrogen Atoms3
Sulfur Atoms2

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