2-(2,4-Dichloro-6-fluorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane CAS 1192002-89-3
| CAS No. | 1192002-89-3 |
| Molecular Formula | C12H14BCl2FO2 |
| Molecular Weight | 290.95 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 2-(2,4-Dichloro-6-fluorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (C12H14BCl2FO2) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
2-(2,4-Dichloro-6-fluorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 1192002-89-3) is a high-purity analytical reference standard with the molecular formula C12H14BCl2FO2 and a molecular weight of 290.95 g/mol.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 2-(2,4-Dichloro-6-fluorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H14BCl2FO2 |
| Molecular Weight | 290.95 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | F/Cl-containing |
Related Dichloro Standards
- 2-(3,5-Dichloro-4-fluorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 1092485-88-5)
- 4,5-Dichloro-2-fluorobenzeneboronic acid pinacol ester, 97% (CAS 1116681-96-9)
- 2-(2,4-Dichloro-3-fluorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 1165935-90-9)
- 2-(3,4-Dichloro-2-fluorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 1165935-92-1)
- 2-(3,4-Dichloro-5-fluorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 1437779-89-9)
- 2-(2,3-Dichloro-5-fluorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 1799938-17-2)
- 2-(2,5-Dichloro-3-fluorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 2121515-31-7)
- 2-(2,6-Dichloro-4-fluorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 2121514-25-6)
Recommended Standards
- 2-Bromo-6-chloropyridine-4-sulfonyl chloride (CAS 1261655-38-2)
- 6-Bromo-2-chloropyridine-3-sulfonyl chloride (CAS 1261662-60-5)
- 5-Bromo-2-chloropyridine-3-sulfonyl chloride (CAS 1146290-19-8)
- 5-Bromo-4-chloropyridine-3-sulfonyl chloride (CAS 1352522-70-3)
- Carbamic acid, N-[(1S,2S)-2-methyl-1-[[(1-methylethyl)amino]carbonyl]butyl]-, phenylmethyl ester (CAS 1820581-62-1)
- 2-(2-Oxo-1,3-diazinan-1-yl)acetic acid (CAS 1049873-89-3)
- Methyl 5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2,3-dihydro-1H-indene-1-carboxylate (CAS 1423700-47-3)
- 3-Chloro-5,6-dihydro-1H-cyclopenta[c]pyridine-1,7(2H)-dione (CAS 2762234-30-8)
- Lodoxamide Impurity N44 (CAS 14994-02-6)
- 8-Chloro-5-fluorochroman-4-amine (CAS 1337158-52-7)
- 4-Methyl-3,4-dihydro-2H-benzo[b][1,4]oxazine-2-carbonitrile (CAS 84831-38-9)
- 6-Ethoxy-1-methyl-3,4-dihydroquinolin-2(1H)-one (CAS 368834-35-9)
- 4-(4H-1,2,4-Triazol-4-yl)piperidine dihydrochloride (CAS 1609407-68-2)
- Semaglutide impurity 62 (CAS CATO-C4X-222662)
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