5-(Benzyloxy)-2-(hydroxymethyl)-3-iodopyridin-4(1H)-one CAS 1192263-75-4
| CAS No. | 1192263-75-4 |
| Molecular Formula | C13H12INO3 |
| Molecular Weight | 357.14 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 5-(Benzyloxy)-2-(hydroxymethyl)-3-iodopyridin-4(1H)-one (C13H12INO3) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, iodine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
5-(Benzyloxy)-2-(hydroxymethyl)-3-iodopyridin-4(1H)-one (CAS 1192263-75-4) is a high-purity analytical reference standard with the molecular formula C13H12INO3 and a molecular weight of 357.14 g/mol.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C13H12INO3 |
| Molecular Weight | 357.14 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | I-containing |
| Nitrogen Atoms | 1 |
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Recommended Standards
- 2-Iodo-3-(2,2,2-trifluoroethyl)benzo[b]thiophen-7-amine (CAS 2903922-15-4)
- Ethyl 3-iodo-2-methyl-4-oxo-1,4-dihydroquinoline-6-carboxylate (CAS 1330755-92-4)
- [(2-Bromo-4-methyl-phenyl)-difluoro-methyl]-phosphonic acid diethyl ester (CAS 863977-42-8)
- 1-(2,4-Dichloro-5-methoxyphenyl)-5-(2,6-difluorophenyl)-1H-tetrazole (CAS 338961-28-7)
- 2-cyclohexylidenmalononitrile (CAS 4354-73-8)
- 6-bromo-4-fluoro-3H-1,3-benzoxazol-2-one (CAS 1780002-65-4)
- 5-Aminocyclohexa-1,3-dienecarboxylic acid hydrochloride (CAS 59556-17-1)
- 2-(Pyridin-4-yl)thiazole (CAS 53911-40-3)
- Decyl 2-chloroacetate (CAS 6974-05-6)
- 2-Bromomethyl-7-fluoro-benzo[b]thiophene (CAS 102246-39-9)
- 3,4-diethyl 6-chloropyridine-3,4-dicarboxylate (CAS 1643842-62-9)
- 3-(Dimethylamino)-1-(thiophen-2-yl)prop-2-en-1-one (CAS 34772-98-0)
- 2-[4-(1H-imidazol-1-yl)phenyl]acetic acid hydrochloride (CAS 1955531-31-3)
- Semaglutide impurity 49 (CAS CATO-C4X-222649)
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