Methyl 5-chloro-1H-imidazole-4-carboxylate CAS 1192372-11-4
| CAS No. | 1192372-11-4 |
| Molecular Formula | C5H5ClN2O2 |
| Molecular Weight | 160.56 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 160.56 g/mol gives Methyl 5-chloro-1H-imidazole-4-carboxylate distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Methyl 5-chloro-1H-imidazole-4-carboxylate (CAS 1192372-11-4), molecular formula C5H5ClN2O2 and molecular weight 160.56 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, Methyl 5-chloro-1H-imidazole-4-carboxylate (C5H5ClN2O2) contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 4.0, corresponding to approximately 4 ring(s) or double-bond equivalent(s). With a molecular weight of 160.56 g/mol, it falls into the medium-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C5H5ClN2O2 |
| Molecular Weight | 160.56 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Methyl Standards
- 4-Chloro-1h-pyrazole-3-carbohydrazide (CAS 1005584-54-2)
- 5-Chloro-2-methyl-1H-imidazole-4-carboxylic acid (CAS 1093261-72-3)
- 5-chloro-3-methyl-1H-pyrazole-4-carboxylic acid (CAS 1093414-62-0)
- 4-Chloro-6-methoxypyridazin-3(2H)-one (CAS 113707-82-7)
- 5-Chloro-6-methoxypyridazin-3(2H)-one (CAS 113707-83-8)
- 5-Chloro-1-methyl-1H-pyrazole-3-carboxylic acid, 97% (CAS 1173246-76-8)
- methyl 5-chloro-1H-imidazole-2-carboxylate (CAS 1211589-29-5)
- 3-Chloro-N-methyl-1H-1,2,4-triazole-5-carboxamide (CAS 1232800-16-6)
Recommended Standards
- Methyl 5-chlorofuran-3-carboxylate (CAS 116668-70-3)
- (4-amino-6-chloro-1,3,5-triazin-2-yl)methanol (CAS 1139245-31-0)
- 4-Chloro-5-methyl-1h-imidazole-2-carboxylic acid (CAS 125001-21-0)
- 2-Chloro-5-hydroxy-3-methylpyrimidin-4(3H)-one (CAS 1333240-10-0)
- 2-(1,4,5,6-Tetrahydropyrimidin-2-yl)benzenethiol (CAS 53440-32-7)
- 3-((3-Bromophenyl)amino)propanamide (CAS 856839-26-4)
- 3-(5-Methyl-1H-tetrazol-1-yl)benzoic acid (CAS 799262-37-6)
- 6-(Dimethylamino)-9-(4-Methylbenzyl)-2-(Trifluoromethyl)-9H-Purine (CAS 117860-34-1)
- Pyrrolidin-1-yl(pyrrolidin-2-yl)methanone (CAS 202990-49-6)
- 4-Fluoro-2-methyl-1-(methylsulfonyl)benzene (CAS 828270-62-8)
- Tizoxanide Sulfate (CAS 1391053-06-7)
- N'-(2-(1H-pyrrol-1-yl)benzoyl)-4-bromobenzenesulfonohydrazide (CAS 478063-14-8)
- 4-Amino-8-methylquinoline-3-carboxylic acid (CAS 1234857-01-2)
- Des-Ser32-Tirzepatide (CAS CATO-CPTD788942)
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