(4,5-Bis(benzyloxy)-2-chlorophenyl)boronic acid CAS 1192737-16-8
| CAS No. | 1192737-16-8 |
| Molecular Formula | C20H18BClO4 |
| Molecular Weight | 368.62 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including (4,5-Bis(benzyloxy)-2-chlorophenyl)boronic acid.
(4,5-Bis(benzyloxy)-2-chlorophenyl)boronic acid (CAS 1192737-16-8) is a high-purity analytical reference standard with the molecular formula C20H18BClO4 and a molecular weight of 368.62 g/mol.
Structurally, (4,5-Bis(benzyloxy)-2-chlorophenyl)boronic acid (C20H18BClO4) contains a flavonoid core, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 11.5, corresponding to approximately 11 ring(s) or double-bond equivalent(s). With a molecular weight of 368.62 g/mol, it falls into the moderately-high-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C20H18BClO4 |
| Molecular Weight | 368.62 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | Cl-containing |
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Recommended Standards
- 10-DOXYL-nonadecane, free radical 101829-05-4 4,4-Dimethyl-2,2-dinonyl-3-oxazolidinyloxy, free radical (CAS 101829-05-4)
- (3-(4-(Tert-butoxycarbonyl)piperazine-1-carbonyl)-4-chlorophenyl)boronic acid (CAS 1704082-12-1)
- Bromfenac Impurity 75 (CAS 91715-34-3)
- (4-(4-(Tert-butoxycarbonyl)piperazine-1-carbonyl)-3-chlorophenyl)boronic acid (CAS 1704097-56-2)
- (2E)-1-(3-{3-[(2-chloro-6-fluorophenyl)methoxy]phenyl}-1H-pyrazol-1-yl)-3-[4-(3-fluoropropoxy)phenyl]prop-2-en-1-one (CAS 477711-76-5)
- 2-{[(1-ethyl-3-methyl-1h-pyrazol-4-yl)methyl]amino}ethan-1-ol (CAS 1172946-15-4)
- tert-butyl 4-(2-((methylsulfonyl)oxy)-1-(2-phenyl-1H-benzo[d]imidazol-1-yl)ethyl)piperidine-1-carboxylate (CAS 2444007-35-4)
- 2-amino-5,5-dimethylhexanamide hydrochloride (CAS 1786251-60-2)
- 4-(Cyclopropanesulfonamidomethyl)benzoic acid (CAS 956325-61-4)
- 1-(4-Ethyl-4-hydroxypiperidin-1-yl)-3,3,3-trifluoropropan-1-one (CAS 2159331-93-6)
- n-(Cyclopropylmethyl)-2-ethoxyaniline (CAS 1156171-00-4)
- 4-Chlorophthalazine-1-carbonitrile (CAS 124433-95-0)
- 1H-pyrido[2,3-b][1,4]thiazin-2(3H)-one (CAS 18504-81-9)
- (Des-Thr?)-Glucagon trifluoroacetate salt (CAS 1802078-27-8)
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