(3,4,5-Trifluorophenyl)methanesulfonyl chloride CAS 1194375-48-8
| CAS No. | 1194375-48-8 |
| Molecular Formula | C7H4ClF3O2S |
| Molecular Weight | 244.62 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO supplies (3,4,5-Trifluorophenyl)methanesulfonyl chloride (CAS 1194375-48-8), a certified reference material (molecular formula C7H4ClF3O2S, MW 244.62 g/mol) for analytical method development and quality control.
Structurally, (3,4,5-Trifluorophenyl)methanesulfonyl chloride (C7H4ClF3O2S) contains a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system. The molecule exhibits a degree of unsaturation (DBE) of 4.0, corresponding to approximately 4 ring(s) or double-bond equivalent(s). With a molecular weight of 244.62 g/mol, it falls into the medium-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a certified reference material (CRM), (3,4,5-Trifluorophenyl)methanesulfonyl chloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C7H4ClF3O2S |
| Molecular Weight | 244.62 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | F/Cl-containing |
| Sulfur Atoms | 1 |
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- 3-Bromo-5,7-dichloro-1-methyl-1H-pyrazolo[4,3-d]pyrimidine (CAS 1033444-08-4)
- (R)-2-Amino-3-(4-fluorophenyl)propan-1-ol hydrochloride (CAS 2102410-90-0)
- 4-Chloro-6-ethyl-1,3,5-triazin-2-amine (CAS 30369-28-9)
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