5-Chloro-6-nitro-1H-indazol-3(2H)-one CAS 1194733-75-9
| CAS No. | 1194733-75-9 |
| Molecular Formula | C7H4ClN3O3 |
| Molecular Weight | 213.58 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 5-Chloro-6-nitro-1H-indazol-3(2H)-one.
5-Chloro-6-nitro-1H-indazol-3(2H)-one (CAS 1194733-75-9), molecular formula C7H4ClN3O3 and molecular weight 213.58 g/mol, is a CATO reference standard with documented purity and traceability.
5-Chloro-6-nitro-1H-indazol-3(2H)-one (C7H4ClN3O3) contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 5-Chloro-6-nitro-1H-indazol-3(2H)-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C7H4ClN3O3 |
| Molecular Weight | 213.58 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Chloro Standards
- 4-Chloro-3-(4H-1,2,4-triazol-4-yl)-1H-pyrazole-5-carboxylic acid (CAS 1234342-77-8)
- 5-Chloro-6-nitro-1,3-benzoxazol-2-amine (CAS 1326810-85-8)
- 7-Chloro-5-nitro-1,3-benzoxazol-2-amine (CAS 1820717-50-7)
- 4-Chloro-6-nitro-1,3-dihydro-2H-benzo[d]imidazol-2-one (CAS 463315-69-7)
- 5-Chloro-6-nitro-1H-benzo[d]imidazol-2(3H)-one (CAS 60713-78-2)
- 6-Chloro-4-nitro-1,2-dihydro-3H-indazol-3-one (CAS 885519-35-7)
- 2-[4-chloro-3-(trifluoromethyl)-1h-pyrazol-1-yl]ethan-1-amine (CAS 1006473-61-5)
- 7-Chloro-5-fluoro-1H-indole-2-carboxylic acid (CAS 1126084-31-8)
Recommended Standards
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- 2-Ethyl-4-isopropoxyphenol (CAS 1243453-44-2)
- 4-Chloro-6-(1-methylhydrazinyl)pyrimidin-5-amine (CAS 89416-26-2)
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- 4-(3-Fluoro-4-methoxyphenyl)butanal (CAS 1339862-32-6)
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