6-Chlorofuro[2,3-b]pyridin-3(2H)-one CAS 1196146-87-8
| CAS No. | 1196146-87-8 |
| Molecular Formula | C7H4ClNO2 |
| Molecular Weight | 169.57 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 6-Chlorofuro[2,3-b]pyridin-3(2H)-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
6-Chlorofuro[2,3-b]pyridin-3(2H)-one (CAS 1196146-87-8) is a high-purity analytical reference standard with the molecular formula C7H4ClNO2 and a molecular weight of 169.57 g/mol.
The molecular framework of 6-Chlorofuro[2,3-b]pyridin-3(2H)-one (C7H4ClNO2) is characterized by an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C7H4ClNO2 |
| Molecular Weight | 169.57 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Chlorofuro Standards
- 2-Chlorofuro[3,4-b]pyridin-7(5H)-one (CAS 1352886-74-8)
- 6-Chlorofuro[3,4-c]pyridin-3(1H)-one, >97% (CAS 1352893-24-3)
- 6-Chlorofuro[3,2-b]pyridin-3(2H)-one (CAS 1400683-14-8)
- 2-Chlorofuro[2,3-d]pyrimidin-4-amine (CAS 1784865-05-9)
- 6-Chlorofuro[3,4-c]pyridin-1(3H)-one (CAS 1823366-46-6)
- 2-Chlorofuro[3,2-d]pyrimidin-4-amine (CAS 1824464-79-0)
- 3-Chlorofuro[3,4-b]pyridin-5(7H)-one (CAS 868636-46-8)
- 5-chlorofuro[2,3-c]pyridin-3-one (CAS 1211591-96-6)
Recommended Standards
- 7-Chloro-2-methyloxazolo[5,4-d]pyrimidine (CAS 118767-93-4)
- 4-Chloroisoxazolo[4,5-c]pyridin-3-amine (CAS 1242515-54-3)
- 7-Chloro-3H-imidazo[4,5-b]pyridine 4-oxide (CAS 115953-98-5)
- (2-Amino-6-chloropyrimidin-4-yl)cyanamide (CAS 1255147-20-6)
- 2-(7-Fluoro-2-methyl-1H-indol-3-yl)ethanamine oxalate (CAS 1177312-91-2)
- benzyl N-(3-azabicyclo[4.1.0]heptan-6-yl)carbamate (CAS 1893960-00-3)
- Fmoc-N-Me-D-Asn-OH (CAS 2044709-67-1)
- 5-Acetylpyrimidine (CAS 10325-70-9)
- N-(3-Chlorophenyl)-2-((5-cyclohexyl-4-phenyl-4H-1,2,4-triazol-3-yl)thio)acetamide (CAS 332870-47-0)
- 2-(Tert-butylamino)nicotinic acid (CAS 460044-25-1)
- N,N-Dimethyl-1H-1,2,4-triazole-1-acetamide (CAS 81041-92-1)
- 2'-(N,N-dimethylsulfamoyl)-5-fluoro-[1,1'-biphenyl]-3-carboxylic acid (CAS 1261996-26-2)
- N-Methyl-3-(methylamino)butanamide (CAS 857779-89-6)
- Neuroendocrine Regulatory Peptide-4 (human, mouse, rat) (H-7266.1000) (CAS 922704-18-5)
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