2-Amino-4-bromo-6-(trifluoromethyl)pyridine CAS 1196147-49-5

Purity 97%+In StockPharmaceutical Standards
CAS No.1196147-49-5
Molecular FormulaC6H4BrF3N2
Molecular Weight241.01 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2-Amino-4-bromo-6-(trifluoromethyl)pyridine CAS 1196147-49-5 chemical structure

Description

The occurrence of 2-Amino-4-bromo-6-(trifluoromethyl)pyridine is closely related to a nitrile group, fluorine/bromine substitution, an aromatic ring system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

2-Amino-4-bromo-6-(trifluoromethyl)pyridine (CAS 1196147-49-5) is a high-purity analytical reference standard with the molecular formula C6H4BrF3N2 and a molecular weight of 241.01 g/mol.

The molecular framework of 2-Amino-4-bromo-6-(trifluoromethyl)pyridine (C6H4BrF3N2) is characterized by a nitrile group, fluorine/bromine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

CATO manufactures 2-Amino-4-bromo-6-(trifluoromethyl)pyridine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC6H4BrF3N2
Molecular Weight241.01 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)4.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1989
Halogen ContentF/Br-containing
Nitrogen Atoms2

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