N,2-Dimethyl-6-(trifluoromethyl)pyrimidin-4-amine CAS 1196156-12-3
| CAS No. | 1196156-12-3 |
| Molecular Formula | C7H8F3N3 |
| Molecular Weight | 191.15 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 191.15 g/mol gives N,2-Dimethyl-6-(trifluoromethyl)pyrimidin-4-amine distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies N,2-Dimethyl-6-(trifluoromethyl)pyrimidin-4-amine (CAS 1196156-12-3), a certified reference material (molecular formula C7H8F3N3, MW 191.15 g/mol) for analytical method development and quality control.
The molecular framework of N,2-Dimethyl-6-(trifluoromethyl)pyrimidin-4-amine (C7H8F3N3) is characterized by a nitrile group, fluorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C7H8F3N3 |
| Molecular Weight | 191.15 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related N Standards
- 1-(1,4-Dimethyl-1H-Pyrrol-2-Yl)-2,2,2-Trifluoroethanone (CAS 128887-06-9)
- 1-(1,2-Dimethyl-1H-pyrrol-3-yl)-2,2,2-trifluoroethanone (CAS 144219-83-0)
- 1-(3,5-Dimethyl-1H-Pyrrol-2-Yl)-2,2,2-Trifluoroethanone (CAS 151464-88-9)
- 1-(1,5-Dimethyl-1H-pyrrol-2-yl)-2,2,2-trifluoroethanone (CAS 74889-29-5)
- 1-(2,4-Dimethyl-1H-pyrrol-3-yl)-2,2,2-trifluoroethanone (CAS 202286-38-2)
- 1,6-Dimethyl-4-(trifluoromethyl)pyridin-2(1H)-one (CAS 343981-56-6)
- 5-(Dimethyl-1,2-oxazol-4-yl)furan-2-carbaldehyde (CAS 1263777-80-5)
- (2,2-Dimethyl-5-nitro-1,3-dioxan-5-yl)methanol (CAS 4728-14-7)
Recommended Standards
- 2-(trifluoromethyl)-4H,5H,6H,7H-pyrazolo[1,5-a]pyrazine (CAS 1196154-97-8)
- (R)-2-amino-2-(2,4,5-trifluorophenyl)ethan-1-ol (CAS 1212857-75-4)
- 3-Oxo-3-(1-(trifluoromethyl)cyclobutyl)propanenitrile (CAS 1188909-23-0)
- (S)-2-amino-2-(2,3,4-trifluorophenyl)ethan-1-ol (CAS 1212986-10-1)
- 2-(Methylthio)quinoline-8-thiol (CAS 89647-37-0)
- n-(4-Chlorophenyl)-2-(naphthalen-2-ylsulfanyl)acetamide (CAS 321945-88-4)
- (3-Chloro-4-fluorophenyl)(thiazol-2-yl)methanone (CAS 1443342-65-1)
- 2,3-Dibromo-5-fluorobenzotrifluoride (CAS 1027511-90-5)
- 3-(1H-pyrazol-1-yl)propan-1-amine dihydrochloride (CAS 848655-53-8)
- 3-Ethyl-2-phenethylpyrrolidine (CAS 525537-33-1)
- 1-Phenyl-1h-imidazole-2-thiol (CAS 17452-09-4)
- 13595-43-2 N-(3-aMinopropyl)-N-butyl-N-MethylaMine N1-butyl-N1-methylpropane-1,3-diamine (CAS 13595-43-2)
- Benzo[f][1,4]thiazepine-3,5(2H,4H)-dione (CAS 92970-91-7)
- Acetyl-(Leu28·31)-Neuropeptide Y (24-36) (CAS 155709-24-3)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com