2-(4-(2,6-Difluorophenoxy)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane CAS 1196396-03-8
| CAS No. | 1196396-03-8 |
| Molecular Formula | C18H19BF2O3 |
| Molecular Weight | 332.15 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 332.15 g/mol gives 2-(4-(2,6-Difluorophenoxy)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies 2-(4-(2,6-Difluorophenoxy)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 1196396-03-8), a certified reference material (molecular formula C18H19BF2O3, MW 332.15 g/mol) for analytical method development and quality control.
The molecular framework of 2-(4-(2,6-Difluorophenoxy)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (C18H19BF2O3) is characterized by a steroid core, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C18H19BF2O3 |
| Molecular Weight | 332.15 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | F-containing |
Related Difluorophenoxy Standards
- 2-(3,5-Difluorophenoxy)-1-(4-phenylpiperazin-1-yl)ethan-1-one (CAS 866153-14-2)
- 2-(2,4-Difluorophenoxy)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine (CAS 1105663-76-0)
- (5E)-5-{[2-(3,4-difluorophenoxy)phenyl]methylidene}-1,3-thiazolidine-2,4-dione (CAS 1164459-32-8)
- 6-(2,4-Difluorophenoxy)-8-methyl-2-(methylthio)pyrido[2,3-d]pyrimidin-7(8H)-one (CAS 449811-12-5)
- 4-(2,4-difluorophenoxy)-2-(trifluoromethyl)quinazoline (CAS 337924-97-7)
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- N-(6-(2,4-Difluorophenoxy)Indan-5-ylMethanesulfonamide (CAS 81614-86-0)
- 4-(2,4-Difluorophenoxy)-2-(methylsulfanyl)-6-(trifluoromethyl)pyrimidine (CAS 477855-98-4)
Recommended Standards
- Benzonitrile, 3-bromo-4-(4-formyl-2-methoxyphenoxy)- (CAS 1055361-87-9)
- 1-(4-Bromophenyl)-5-(1h-pyrrol-1-yl)-1h-pyrazole-4-carboxylic acid (CAS 1224164-73-1)
- Methyl 3-(cyclopropylamino)-2-(2,4-dichloro-5-fluorobenzoyl)acrylate (CAS 105392-26-5)
- 1-(2-Bromophenyl)-5-(1H-pyrrol-1-yl)-1H-pyrazole-4-carboxylic acid (CAS 1232693-52-5)
- 2-(4-Benzylpiperazin-1-yl)isonicotinonitrile (CAS 1016862-98-8)
- 1,3-Bis(di-tert-butylphosphino)propane (CAS 121115-33-1)
- 2-Methyl-4-pyrimidinyl-boronic Acid (CAS 647853-31-4)
- (2-Methyl-4-(n-propylsulfamoyl)phenyl)boronic acid (CAS 1217501-47-7)
- 9-Oxa-3-azabicyclo[3.3.1]nonane hydrochloride (CAS 1947317-74-9)
- 2-{7-methyl-3H-imidazo[4,5-b]pyridin-2-yl}acetonitrile (CAS 577777-13-0)
- 6-Methoxy-5-nitroindoline (CAS 23772-40-9)
- 7-bromoimidazo[1,2-a]pyridine-2-carboxylic acid (CAS 1019018-46-2)
- (1R,2R)-2',3'-Dihydrospiro[cyclopropane-1,1'-inden]-2-amine (CAS 2037171-98-3)
- Neuropeptide W-23 (human) (CAS 383415-79-0)
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