4-((2-Fluoro-5-methylphenyl)sulfonyl)piperazin-2-one CAS 1197520-81-2
| CAS No. | 1197520-81-2 |
| Molecular Formula | C11H13FN2O3S |
| Molecular Weight | 272.30 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
4-((2-Fluoro-5-methylphenyl)sulfonyl)piperazin-2-one (CAS 1197520-81-2), molecular formula C11H13FN2O3S and molecular weight 272.30 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 4-((2-Fluoro-5-methylphenyl)sulfonyl)piperazin-2-one (C11H13FN2O3S) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
CATO manufactures 4-((2-Fluoro-5-methylphenyl)sulfonyl)piperazin-2-one under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C11H13FN2O3S |
| Molecular Weight | 272.30 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
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Recommended Standards
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- Methyl 2,6-dimethoxypyridine-4-carboxylate (CAS 52606-00-5)
- N-(Benzo[d]isothiazol-3-yl)acetamide (CAS 29109-77-1)
- 1-(1-Benzhydrylazetidin-3-yl)pyrrolidine (CAS 55438-67-0)
- Methyl 8-(tert-butyl)-4-oxo-1,4-dihydroquinoline-2-carboxylate (CAS 1410367-90-6)
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- N-(2-Oxo-1,2,5,6-tetrahydro-4H-pyrrolo[3,2,1-ij]quinolin-8-yl)benzamide (CAS 898463-44-0)
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- 3-(4-Fluoro-2-methylphenyl)-3-oxopropanenitrile (CAS 705278-81-5)
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Why CATO?
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