3-Methoxy-2-(trifluoromethyl)phenylboronic acid CAS 1198181-64-4
| CAS No. | 1198181-64-4 |
| Molecular Formula | C8H8BF3O3 |
| Molecular Weight | 219.95 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 3-Methoxy-2-(trifluoromethyl)phenylboronic acid.
3-Methoxy-2-(trifluoromethyl)phenylboronic acid (CAS 1198181-64-4) is a high-purity analytical reference standard with the molecular formula C8H8BF3O3 and a molecular weight of 219.95 g/mol.
The molecular framework of 3-Methoxy-2-(trifluoromethyl)phenylboronic acid (C8H8BF3O3) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 3-Methoxy-2-(trifluoromethyl)phenylboronic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H8BF3O3 |
| Molecular Weight | 219.95 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.5 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | F-containing |
Related Methoxy Standards
- 3-Methoxy-4-(trifluoromethyl)phenylboronic Acid (CAS 1004775-33-0)
- (2-Methoxy-3-(trifluoromethyl)phenyl)boronic acid (CAS 1072946-62-3)
- 2-Methoxy-6-(trifluoromethyl)phenylboronic Acid (CAS 1310384-19-0)
- (5-Methoxy-2-(trifluoromethyl)phenyl)boronic acid (CAS 1437787-72-8)
- 4-Methoxy-3-(trifluoromethyl)phenylboronic Acid (CAS 149507-36-8)
- (4-Methoxy-2-(trifluoromethyl)phenyl)boronic acid (CAS 313546-16-6)
- 2-Methoxy-4-(trifluoromethyl)phenylboronic Acid (CAS 312936-89-3)
- 2-Methoxy-5-(trifluoromethyl)phenylboronic acid (CAS 240139-82-6)
Recommended Standards
- 5-Methyl-2-(trifluoromethoxy)phenylboronic acid (CAS 1079402-45-1)
- (4-(2,2,2-Trifluoro-1-hydroxyethyl)phenyl)boronic acid (CAS 1346526-55-3)
- (3-Methyl-5-(trifluoromethoxy)phenyl)boronic acid (CAS 1417301-61-1)
- 1,4-Dibromobutane-2,2,3,3-d4 (CAS 52089-63-1)
- Methyl 4-iodobutyrate (CAS 14273-85-9)
- N-(4-acetylphenyl)-2-(4-chlorophenoxy)acetamide (CAS 303992-57-6)
- [4-Fluoro-3-(tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]methanol (CAS 1333264-06-4)
- 1-[2-(2-Methoxyphenyl)ethyl]-5-oxo-3-pyrrolidinecarboxylic acid (CAS 407634-12-2)
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- Semaglutide impurity 55 (CAS CATO-C4X-222655)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com