Rivaroxaban Impurity 113 CAS 119835-88-0
| CAS No. | 119835-88-0 |
| Molecular Formula | C11H11NO4 |
| Molecular Weight | 221.21 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Rivaroxaban Impurity 113 (CAS 119835-88-0, C11H11NO4) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Rivaroxaban Impurity 113 (C11H11NO4) is characterized by an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Rivaroxaban Impurity 113 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C11H11NO4 |
| Molecular Weight | 221.21 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Nitrogen Atoms | 1 |
Related Rivaroxaban Standards
- Rivaroxaban Impurity 133 (CAS 130155-41-8)
- Rivaroxaban Impurity 7 (CAS 186348-58-3)
- Rivaroxaban Impurity 110 (CAS CATO-C4X-1090110)
- Rivaroxaban Impurity 48 (CAS 62457-35-6)
- Rivaroxaban Impurity 213 (CAS CATO-C4X-1090213)
- Rivaroxaban Impurity 81 (CAS 1394169-92-6)
- Rivaroxaban Impurity 37 (CAS 446292-04-2)
- Rivaroxaban Impurity 58 (CAS 845729-43-3)
Recommended Standards
- Cyclic N-Acetyl-D-mannosamine (CAS 7772-94-3)
- Indacaterol Impurity 33 (CAS CATO-C4X-150033)
- N-((2S,3R,4R,5S,6R)-2,4,5-Trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-3-yl)acetamide (CAS 10036-64-3)
- Indacaterol Impurity 91 (CAS CATO-C4X-150091)
- Dabrafenib Impurity 21 (CAS CATO-C4X-303321)
- Flurbiprofen Impurity 169 (CAS CATO-C4X-1444169)
- Salbutamol Impurity 110 (CAS 345322-10-3)
- 2-Hydroxycyclopentane-1-carbonitrile (CAS 57836-12-1)
- 1-phenyl-5-(propan-2-yl)-1H-pyrazol-4-amine hydrochloride (CAS 1795506-87-4)
- 2-Bromo-6-fluoro-3-isopropylbenzaldehyde (CAS 2158302-47-5)
- 3-(3-Bromophenyl)-3,5-dichloropropiophenone (CAS 898760-75-3)
- Isopropyl 4,6-dimethyl-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate (CAS 333439-11-5)
- 2-(Methylsulfanyl)ethanimidamide hydrochloride (CAS 105324-22-9)
- Tirzepatide Impurity 15 (CAS CATO-C4X-324015)
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