6-Phenyl-2-(piperazin-1-yl)nicotinonitrile CAS 1198475-33-0
| CAS No. | 1198475-33-0 |
| Molecular Formula | C16H16N4 |
| Molecular Weight | 264.33 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
6-Phenyl-2-(piperazin-1-yl)nicotinonitrile (CAS 1198475-33-0) is a high-purity analytical reference standard with the molecular formula C16H16N4 and a molecular weight of 264.33 g/mol.
The molecular framework of 6-Phenyl-2-(piperazin-1-yl)nicotinonitrile (C16H16N4) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO manufactures 6-Phenyl-2-(piperazin-1-yl)nicotinonitrile under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C16H16N4 |
| Molecular Weight | 264.33 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Nitrogen Atoms | 4 |
Related Phenyl Standards
- 4-(6-Methyl-2-(piperazin-1-yl)pyrimidin-4-yl)morpholine (CAS 1511906-37-8)
- Benzyl (2-(piperazin-1-yl)ethyl)carbamate (CAS 302557-33-1)
- 6-(Piperazin-1-ylsulfonyl)-1H-indole (CAS 919833-59-3)
- 2-((2-(Piperazin-1-yl)ethyl)thio)-1H-benzo[d]imidazole (CAS 217095-58-4)
- Butyl 4-(Piperazin-1-yl)benzoate (CAS 86620-18-0)
- 3-(Piperazin-1-yl)tetrahydro-2h-thiopyran-3-carboxylic acid 1,1-dioxide (CAS 1404871-87-9)
- Phenyl(4-piperazin-1-ylphenyl)methanone (CAS 482308-61-2)
- 4-(1-Acetyl-piperazin-2-yl)-benzoic acid methyl ester (CAS 1316218-72-0)
Recommended Standards
- 4-Methyl-5-(3-(thiophen-2-yl)-1,2,4-oxadiazol-5-yl)thiazol-2-amine (CAS 1179479-91-4)
- Stilbamidine (CAS 122-06-5)
- 4-{[3-(thiophen-3-yl)-1,2,4-oxadiazol-5-yl]methyl}-1,3-thiazol-2-amine (CAS 1155056-02-2)
- N4-(2-Ethylphenyl)quinazoline-4,6-diamine (CAS 1428063-84-6)
- 4,9-Dihydroxy-2,3-dimethyl-8-oxo-5,8-dihydro-3H-imidazo[4,5-g]quinazoline-6-carbaldehyde (CAS 121732-23-8)
- 3-[(naphthalen-1-yloxy)methyl]benzoic acid (CAS 438465-54-4)
- (+)-Indolactam V (CAS 90365-56-3)
- 3-Amino-2,2-difluoropropan-1-ol hydrochloride (CAS 1314395-95-3)
- (E)-5-(Methoxy(methyl)amino)-1-phenylpent-1-en-3-one (CAS 1356089-40-1)
- 4-Bromo-2-ethoxyaniline (CAS 57279-73-9)
- (4-(Azetidin-1-ylmethyl)phenyl)(3,4-dimethylphenyl)methanone (CAS 898756-69-9)
- 1-methanesulfonylazetidine-2-carbohydrazide (CAS 1779481-68-3)
- Pantoprazole EP Impurity D and F（USP Impurity D and F） (CAS CATO-C4X-139910)
- Semaglutide Impurity 160 (x TFA Salt) (CAS CATO-C4X-2226160)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com