1-(4-Fluorophenyl)-2-methylpropan-2-amine CAS 1200-27-7
| CAS No. | 1200-27-7 |
| Molecular Formula | C10H14FN |
| Molecular Weight | 167.22 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 1-(4-Fluorophenyl)-2-methylpropan-2-amine.
CATO supplies 1-(4-Fluorophenyl)-2-methylpropan-2-amine (CAS 1200-27-7), a certified reference material (molecular formula C10H14FN, MW 167.22 g/mol) for analytical method development and quality control.
Structurally, 1-(4-Fluorophenyl)-2-methylpropan-2-amine (C10H14FN) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 4.0, corresponding to approximately 4 ring(s) or double-bond equivalent(s). With a molecular weight of 167.22 g/mol, it falls into the medium-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H14FN |
| Molecular Weight | 167.22 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Fluorophenyl Standards
- 4-(2-Fluorophenyl)butan-1-amine (CAS 1017226-33-3)
- 4-(2-Fluorophenyl)butan-2-amine (CAS 1092924-49-6)
- 4-(3-fluorophenyl)butan-2-amine (CAS 1092924-64-5)
- (S)-1-(2-fluorophenyl)-2-methylpropan-1-amine (CAS 1212854-45-9)
- (S)-1-(2-fluorophenyl)butan-1-amine (CAS 1212922-49-0)
- (S)-1-(4-fluorophenyl)-2-methylpropan-1-amine (CAS 1213511-21-7)
- (R)-1-(4-fluorophenyl)-2-methylpropan-1-amine (CAS 1213827-41-8)
- 1-(2-Fluorophenyl)butan-1-amine (CAS 1225519-40-3)
Recommended Standards
- 1-(3-Fluoro-4-methylphenyl)propan-1-amine (CAS 1184551-53-8)
- 2-(2-Fluoro-5-methylphenyl)propan-2-amine (CAS 1202853-63-1)
- 4-Fluoro-N-isopropyl-2-methylaniline (CAS 117947-29-2)
- 3-((S)-1-amino-2-methylpropyl)benzonitrile (CAS 1212188-96-9)
- 2,5-Dimethyl-1-{2-[7-(naphthalen-2-yl)pyrazolo[1,5-a]pyrimidin-2-yl]thiophen-3-yl}-1H-pyrrole (CAS 439095-77-9)
- Ethyl 4-Chlorobutyrate (CAS 3153-36-4)
- 3-Cyclopropyl-2,2-dimethylpropanal (CAS 1934402-30-8)
- (Z)-3-Chloro-2-formyl-but-2-enoic acid ethyl ester (CAS 31357-78-5)
- (S)-2-(4,5-difluoro-2-nitrophenyl)pyrrolidine (CAS 1213356-52-5)
- 3-(tert-Butyl)-6-fluoro-1,2,3,4-tetrahydroquinoline (CAS 1341670-43-6)
- (2R,3S)-1-benzyl 4-tert-butyl 3-(cyclopropylmethyl)-2-(3,3,3-trifluoropropyl)succinate (CAS 1581734-69-1)
- 9,10-Dioxo-9,10-dihydroanthracene-1,4-diyl bis(4-methylbenzenesulfonate) (CAS 96701-06-3)
- 4-[4-(Dimethylamino)-1-(4’-chlorophenyl)-1-hydroxybutyl]-3-(hydroxymethyl)-benzonitrile (CAS 1076200-05-9)
- [pGlu] Semaglutide (CAS CATO-C4X-2226288)
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